Chen Geng-Ci, Lo Kai-Li, Wu Zhi-Fu, Chan Shun-Ming, Cheng Sheng-Yao, Ko Ching-Lung, Chu Chi-Ming, Tseng Wei-Cheng
Department of Anesthesiology, Tri-Service General Hospital, National Defense Medical Center, No. 325, Section 2, Chenggong Road, Neihu District 114, Taipei City, Taiwan.
Division of Anesthesiology, Tri-Service General Hospital Songshan Branch, National Defense Medical Center, Taipei City, Taiwan.
BMC Anesthesiol. 2025 Apr 12;25(1):181. doi: 10.1186/s12871-025-03040-y.
Postoperative sore throat (POST) is a minor complication of general anesthesia with tracheal intubation but may negatively affect patient satisfaction and postoperative recovery. The shape of the endotracheal tube (ETT) cuff may influence the incidence and severity of POST.
This prospective, randomized, double-blinded study was conducted on 174 female patients with breast cancer. They were randomized into the cylindrical (CYL) (group C) and tapered (TAP) (group T) cuff ETT groups. Data on patient demographics, surgical characteristics, and factors related to tracheal intubation were collected. Furthermore, the incidence and severity of POST at the selected time points were duly recorded for analysis. Other adverse events and anesthesia satisfaction were also documented.
During the 48-h evaluation period, group T exhibited reduced overall incidence of POST compared with group C. The incidence and severity of POST at 1, 6, 12, 24, and 48 h postoperatively were also significantly lower in group T than in group C. No significant difference in subglottic airway injury was observed between the two groups. Postoperative anesthesia satisfaction was higher in group T.
The present study demonstrates that the utilization of a TAP cuff ETT rather than a CYL cuff ETT in patients undergoing breast cancer surgery reduced the incidence and severity of POST. The selection of an appropriate ETT for surgical patients could play a pivotal role in alleviating airway complications, enhancing postoperative recovery, and improving anesthesia satisfaction.
The study was registered at ClinicalTrials.gov (NCT06505850) on 2024-07-17.
术后咽痛（POST）是气管插管全身麻醉的一种轻微并发症，但可能对患者满意度和术后恢复产生负面影响。气管内导管（ETT）套囊的形状可能会影响POST的发生率和严重程度。
本前瞻性、随机、双盲研究纳入了174例乳腺癌女性患者。她们被随机分为圆柱形（CYL）（C组）和锥形（TAP）（T组）套囊ETT组。收集了患者人口统计学、手术特征以及与气管插管相关因素的数据。此外，还适时记录了选定时间点POST的发生率和严重程度以进行分析。同时记录了其他不良事件和麻醉满意度。
在48小时的评估期内，T组的POST总体发生率低于C组。术后1、6、12、24和48小时，T组POST的发生率和严重程度也显著低于C组。两组间声门下气道损伤无显著差异。T组术后麻醉满意度更高。
本研究表明，在接受乳腺癌手术的患者中使用TAP套囊ETT而非CYL套囊ETT可降低POST的发生率和严重程度。为手术患者选择合适的ETT对于减轻气道并发症、促进术后恢复以及提高麻醉满意度可能起着关键作用。
该研究于2024年7月17日在ClinicalTrials.gov（NCT06505850）注册。
