基因组学与运动表现：一门尚未为社会做好准备的新兴学科。
Genomics and athletic performance: an emerging discipline that is not yet ready for society.
作者信息
Psatha Aikaterini, Mitropoulou Christina, Patrinos George P
机构信息
School of Health Sciences, Department of Pharmacy, Laboratory of Pharmacogenomics and Individualized Therapy, University of Patras, Patras, Greece.
The Golden Helix Foundation, London, UK.
出版信息
Hum Genomics. 2025 Apr 12;19(1):40. doi: 10.1186/s40246-025-00751-8.
Genomics of athletic performance is an emerging discipline with a high degree of controversy. With the existing level of evidence, it is both premature and highly risky to exploit current human genomics knowledge to predict exercise and sports performance or enhance existing training methodologies. Until more solid evidence on the influence of genomic variants in athletic performance becomes available, accompanied by regulatory approved genome-guided recommendations, all genetic associations should be restricted from general public access as commercial services, since genomic markers cannot per se predict athletic performance for talent identification, resistance to injuries or the ability to recover from them. Evidently, the complex interplay of genetics with other physical, physiological and even psychological and mental characteristics to produce a world-class athlete is still not understood.
运动表现基因组学是一门新兴学科，存在高度争议。以现有证据水平而言，利用当前人类基因组学知识来预测运动和体育表现或改进现有训练方法既为时过早又风险极高。在获得关于基因组变异对运动表现影响的更确凿证据，并伴有监管部门批准的基因组指导建议之前，所有基因关联信息都应禁止作为商业服务向公众提供，因为基因组标记本身无法预测运动表现，无法用于人才识别、抗损伤能力或从损伤中恢复的能力。显然，基因与其他身体、生理乃至心理和精神特征之间复杂的相互作用，以造就一名世界级运动员，目前仍未被理解。
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