Kaymak Hakan, Mattern Ann-Isabel, Graff Birte, Devenijn Machteld, Seitz Berthold, Schwahn Hartmut
Internationale Innovative Ophthalmochirurgie, Breyer Kaymak Klabe Augenchirurgie, Dusseldorf, Germany.
Gottfried O.H. Naumann-Institute of Epidemiology and Prevention of Myopia, Saarland University, Homburg, Germany.
Ophthalmic Physiol Opt. 2025 Jun;45(4):995-1003. doi: 10.1111/opo.13515. Epub 2025 Apr 12.
To investigate the influence of light modulation conferred by current designs of myopia control spectacles on retinal sensitivity.
Retinal sensitivity and scanning laser ophthalmoscopy (SLO) fundus images were obtained from nine healthy subjects using a Macular Integrity Assessment microperimeter with current myopia control spectacle lenses: MyoCare, Stellest, MiYOSMART and DOT. Respectively powered single vision lenses and a 0.8-grade Bangerter occlusion foil (BF) served as comparative controls.
Using the SLO image, one can visualise the areas of light modulation of the various myopia control lens designs at the level of the retina. Clear zone sizes differ between lens designs, with the DOT lens having the smallest area. Retinal sensitivity in areas of local light modulation was not reduced for the Stellest and MyoCare lenses, but declined with the MiYOSMART lens, suggesting a more prominent local light modulation. The DOT lenses produced a significant reduction in overall retinal sensitivity, although the reduction with the BF was greater. In all instances, retinal sensitivity remained well above the range considered normal for a healthy retina.
None of the lenses tested produced a clinically relevant reduction in retinal sensitivity and all scored significantly better than the lowest (that is, 0.8) grade BF. Given that current myopia control spectacles do not show consistent treatment effects as required to slow progression effectively over extended periods, there appears to be a subtle, yet crucial difference in spatial light modulation among these myopia control spectacle lenses. Seemingly similar lens designs cannot be assumed to have equivalent treatment effects; a thorough assessment of these nuances is essential to ensure accurate claims regarding their long-term efficacy.
研究当前近视控制眼镜设计所赋予的光调制对视网膜敏感度的影响。
使用黄斑完整性评估微视野计，对九名健康受试者佩戴当前的近视控制眼镜镜片（MyoCare、Stellest、MiYOSMART和DOT）时的视网膜敏感度和扫描激光检眼镜（SLO）眼底图像进行采集。分别使用单光镜片和0.8级的班格特遮挡箔（BF）作为对照。
使用SLO图像，可以在视网膜水平可视化各种近视控制镜片设计的光调制区域。不同镜片设计的清晰区大小不同，DOT镜片的面积最小。Stellest和MyoCare镜片在局部光调制区域的视网膜敏感度没有降低，但MiYOSMART镜片使其降低，表明其局部光调制更显著。DOT镜片使整体视网膜敏感度显著降低，尽管BF导致的降低幅度更大。在所有情况下，视网膜敏感度仍远高于健康视网膜的正常范围。
所测试的镜片均未使视网膜敏感度出现具有临床意义的降低，且所有镜片的得分均显著优于最低（即0.8）级的BF。鉴于当前的近视控制眼镜未能如有效减缓长期进展所需那样表现出一致的治疗效果，这些近视控制眼镜镜片在空间光调制方面似乎存在细微但关键的差异。不能认为看似相似的镜片设计具有等效的治疗效果；对这些细微差别进行全面评估对于确保其长期疗效的准确宣称至关重要。
