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科威特老年人认知功能结局的相关因素:一项横断面研究。

Factors associated with cognitive function outcomes among older adults in Kuwait: A cross-sectional study.

作者信息

Albuloshi Thurayya, Kamel Ahmed M, Alsaber Ahmad R, Alawadhi Balqees, Pan Jiazhu, Abd-El-Gawad Wafaa Mostafa, Bouhaimed Manal, Spencer Jeremy P E

机构信息

Palliative Care Center, Kuwait, Ministry of Health, Al Sabah Medical Area, P.O. Box 5, Kuwait City, 13001, Kuwait.

Department of Clinical Pharmacy, Faculty of Pharmacy, Cairo University, Kasr El-Aini, Cairo, 11562, Egypt.

出版信息

BMC Geriatr. 2025 Apr 14;25(1):249. doi: 10.1186/s12877-025-05882-0.

Abstract

BACKGROUND

The number of people living with dementia and/or cognitive impairment worldwide is rising with a negative effect on quality of life for many older adults. This study aims to examine the factors associated with cognitive function among older adults in Kuwait.

METHODS

This cross-sectional study recruited 253 older adults ≥ 60 years from a Geriatric outpatient unit in Kuwait. Cognitive function (dependent variable) was assessed using the Arabic version of the Mini-Mental State Examination (MMSE) with scores < 24 indicative of cognitive impairment. Biochemical, nutritional, clinical, lifestyle, anthropometric, and sociodemographic independent variables were included.

RESULTS

A normal MMSE score was reported for 51.0% (n = 129) of the sample, with 34.7% and 14.2% of participants having mild and moderate/severe cognitive impairment, respectively. Multivariate ordinal logistic regression analysis indicated that Type 2 diabetes was associated with more than double the odds of cognitive impairment (OR = 2.15, 95% CI: 1.19-3.94; P = 0.01). Each additional level of education was associated with a lower likelihood of cognitive impairment (OR = 0.34, 95% CI: 0.26-0.43; P < 0.001).

CONCLUSION

This study identifies key risk factors associated with cognitive impairment in older Kuwaiti adults. These findings underscore the need for targeted interventions to mitigate cognitive decline in aging populations and provide context-specific data to support policy decisions.

摘要

背景

全球患有痴呆症和/或认知障碍的人数正在增加,这对许多老年人的生活质量产生了负面影响。本研究旨在探讨科威特老年人认知功能的相关因素。

方法

这项横断面研究从科威特的一个老年门诊招募了253名60岁及以上的老年人。使用阿拉伯语版简易精神状态检查表(MMSE)评估认知功能(因变量),得分低于24分表明存在认知障碍。纳入了生化、营养、临床、生活方式、人体测量和社会人口统计学等自变量。

结果

样本中有51.0%(n = 129)的人MMSE得分正常,分别有34.7%和14.2%的参与者存在轻度和中度/重度认知障碍。多变量有序逻辑回归分析表明,2型糖尿病与认知障碍几率增加两倍以上相关(比值比=2.15,95%置信区间:1.19-3.94;P = 0.01)。每增加一个教育水平,认知障碍的可能性就会降低(比值比=0.34,95%置信区间:0.26-0.43;P < 0.001)。

结论

本研究确定了科威特老年成年人认知障碍的关键风险因素。这些发现强调了需要有针对性的干预措施来减轻老年人群的认知衰退,并提供特定背景的数据以支持政策决策。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a95/11995643/deb2db06e176/12877_2025_5882_Fig1_HTML.jpg

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