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23岁女性原发性肺支气管内黏液表皮样癌行袖状切除术治疗:病例报告

Primary Pulmonary Endobronchial Mucoepidermoid Carcinoma Treated With Sleeve Resection in a 23-Year-Old Woman: Case Report.

作者信息

Rauniyar Ritika, Sharma Aakriti, Thapaliya Pratikshya, Sapkota Ranjan

机构信息

Department of Cardio-Thoracic and Vascular Surgery, Manmohan Cardio-Thoracic Vascular and Transplant Center Institute of Medicine, Tribhuvan University Kathmandu Nepal.

出版信息

Respirol Case Rep. 2025 Apr 13;13(4):e70173. doi: 10.1002/rcr2.70173. eCollection 2025 Apr.

Abstract

Pulmonary Mucoepidermoid Carcinoma (PMEC) is a rare, slow-growing, low-grade primary intrathoracic cancer of the tracheobronchial tree that manifests as an exophytic endobronchial tumour with luminal obstruction. Radical surgery is the cornerstone of treatment for low-grade PMEC. We report a case of a 23-year-old woman who presented with intermittent haemoptysis. On imaging, an endoluminal mass was seen in the bronchus intermedius, also visualised on bronchoscopy, although biopsies were inconclusive. Final histology after surgical resection revealed a low-grade PMEC with tumour-free margins. The postoperative course was uncomplicated, and no recurrence was evident after 6 months. Lung-preserving sleeve resection for low-grade PMECs with clear margins is a safe and feasible surgery, offering favourable short-term outcomes. Ongoing surveillance will be necessary for longer-term results.

摘要

肺黏液表皮样癌(PMEC)是一种罕见的、生长缓慢的、低级别气管支气管树原发性胸内癌,表现为外生性支气管内肿瘤并伴有管腔阻塞。根治性手术是低级别PMEC治疗的基石。我们报告一例23岁女性,她表现为间歇性咯血。影像学检查发现中间支气管内有腔内肿块,支气管镜检查也可见该肿块,尽管活检结果不明确。手术切除后的最终组织学检查显示为低级别PMEC,切缘无肿瘤。术后过程无并发症,6个月后无复发迹象。对于切缘清晰的低级别PMEC进行肺保留袖状切除术是一种安全可行的手术,具有良好的短期效果。为获得长期结果,持续监测是必要的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f018/11994294/308a8ede1572/RCR2-13-e70173-g001.jpg

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