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创伤性失血性休克的院前血液输注

Prehospital Blood Administration in Traumatic Hemorrhagic Shock.

作者信息

McNeilly Bryan, Samsey Kathleen, Kelly Seth, Pennardt Andre, Guyette Francis X

机构信息

Department of Emergency Medicine, University of Washington, Seattle, Washington, USA.

US Army Medical Center of Excellence, Fort Sam Houston, Texas, USA.

出版信息

J Am Coll Emerg Physicians Open. 2025 Jan 24;6(2):100041. doi: 10.1016/j.acepjo.2024.100041. eCollection 2025 Apr.

DOI:10.1016/j.acepjo.2024.100041
PMID:40236265
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11997682/
Abstract

Following the military's advancement of prehospital blood into the field, civilian prehospital blood programs are becoming more prevalent. However, there are significant differences between civilian and military prehospital operations that should be considered. Civilian prehospital systems also vary widely in terms of resources, transport times, and patient types. Given these variations and the logistical challenges associated with establishing a prehospital blood program, careful consideration of the state of the science is warranted. Although blood is the preferred fluid for patients in hemorrhagic shock, there have only been a few high-quality studies that have examined the efficacy of administering blood in the prehospital setting. Given the conflicting results of these studies, individual medical directors must determine whether the risk-benefit analysis for their system warrants establishing such a resource-intensive operation. Efforts to establish a prehospital blood program should not supersede attempts to optimize the fundamental components of trauma operations and management.

摘要

随着军队将院前输血引入战场,民用院前输血项目正变得越来越普遍。然而,民用和军事院前行动之间存在显著差异,应予以考虑。民用院前系统在资源、转运时间和患者类型方面也存在很大差异。鉴于这些差异以及建立院前输血项目所带来的后勤挑战,有必要仔细考虑科学现状。尽管血液是失血性休克患者的首选液体,但仅有少数高质量研究考察了院前输血的疗效。鉴于这些研究结果相互矛盾,各医疗主管必须确定其系统的风险效益分析是否足以支持开展这样一项资源密集型行动。建立院前输血项目的努力不应取代优化创伤手术和管理基本要素的尝试。

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Prehospital Blood Administration in Traumatic Hemorrhagic Shock.创伤性失血性休克的院前血液输注
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本文引用的文献

1
Removing the barriers to prehospital blood: A roadmap to success.消除院前血液供应障碍:通向成功的蓝图。
J Trauma Acute Care Surg. 2024 Aug 1;97(2S Suppl 1):S138-S144. doi: 10.1097/TA.0000000000004378. Epub 2024 May 1.
2
Implementation of a prehospital whole blood program: Lessons learned.院前全血项目的实施:经验教训
J Am Coll Emerg Physicians Open. 2024 Mar 21;5(2):e13142. doi: 10.1002/emp2.13142. eCollection 2024 Apr.
3
Faster refill in an urban emergency medical services system saves lives: A prospective preliminary evaluation of a prehospital advanced resuscitative care bundle.城市急救医疗服务系统中更快的补液可挽救生命:院前高级复苏治疗包的前瞻性初步评估。
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Whole Blood Resuscitation and Association with Survival in Injured Patients with an Elevated Probability of Mortality.全血复苏与创伤患者高死亡率的相关性研究。
J Am Coll Surg. 2023 Aug 1;237(2):206-219. doi: 10.1097/XCS.0000000000000708. Epub 2023 Apr 11.
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The impact of prehospital whole blood on hemorrhaging trauma patients: A multi-center retrospective study.院前全血对出血性创伤患者的影响:一项多中心回顾性研究。
J Trauma Acute Care Surg. 2023 Aug 1;95(2):191-196. doi: 10.1097/TA.0000000000003908. Epub 2023 Apr 4.
6
Optimal Prehospital Crystalloid Resuscitation Volume in Trauma Patients at Risk for Hemorrhagic Shock.创伤患者出血性休克风险的最佳院前晶体液复苏容量。
J Am Coll Surg. 2023 Aug 1;237(2):183-194. doi: 10.1097/XCS.0000000000000695. Epub 2023 Mar 28.
7
Time to early resuscitative intervention association with mortality in trauma patients at risk for hemorrhage.创伤出血高危患者早期复苏干预时间与死亡率的关系。
J Trauma Acute Care Surg. 2023 Apr 1;94(4):504-512. doi: 10.1097/TA.0000000000003820. Epub 2023 Jan 11.
8
A CIRCULATION-FIRST APPROACH FOR RESUSCITATION OF TRAUMA PATIENTS WITH HEMORRHAGIC SHOCK.一种针对创伤性失血性休克患者复苏的循环优先方法。
Shock. 2023 Jan 1;59(1):1-4. doi: 10.1097/SHK.0000000000002028. Epub 2022 Oct 28.
9
Association of Whole Blood With Survival Among Patients Presenting With Severe Hemorrhage in US and Canadian Adult Civilian Trauma Centers.全血输注与美国和加拿大成人平民创伤中心严重出血患者生存的关联。
JAMA Surg. 2023 May 1;158(5):532-540. doi: 10.1001/jamasurg.2022.6978.
10
Use of Cold-Stored Whole Blood is Associated With Improved Mortality in Hemostatic Resuscitation of Major Bleeding: A Multicenter Study.冷存全血的使用与大出血止血复苏中死亡率的降低有关:一项多中心研究。
Ann Surg. 2022 Oct 1;276(4):579-588. doi: 10.1097/SLA.0000000000005603. Epub 2022 Jul 18.