Lešták Jan, Kynčl Martin, Haninec Pavel, Fůs Martin, Eis Vaclav, Mandys Vaclav
Faculty of Biomedical Engineering, Czech Technical University in Prague, 27201 Kladno, Czech Republic.
Department of Neurosurgery, Charles University, 3rd Faculty of Medicine and University Hospital Královské Vinohrady, 10034 Prague, Czech Republic.
Mol Clin Oncol. 2025 Mar 28;22(6):47. doi: 10.3892/mco.2025.2842. eCollection 2025 Jun.
A case report of a 70-year-old woman who had never suffered from any eye disease is presented. It was found that 2 weeks prior to the ophthalmological examination at another clinic 'something fell' into her right eye; she noticed a decline in the vision of her the left eye. On ophthalmologic examination Visual Acuity, Right Eye (VARE) was 0.4 and Visual Acuity, Left Eye (VALE): fingers at 1 m. Incipient cataracts in both eyes, more on the right. On optic nerve (ON) evaluation, the optic papilla cup-to-disk ratio (C/D) was=0.6 and 0.7, R/L, respectively. A total of 1 month after the first examination VARE was found: 0.4 and VALE: 0.16. The cataracts did not correspond to the decrease in visual acuity. an excavation on the right papilla (C/D=0.6) was found and the left papilla was atrophic (C/D=0.7). Otherwise, the fundus evaluation was normal. Incomplete upper temporal quadrantanopia on the right visual field (VF) and temporal hemianopia extending into the central part on the left VF were identified. An electrophysiological examination (pattern visual evoked responses) showed a marked decrease in amplitudes on the right and no prolongation of P100 latency; a non-excitable reaction was observed in the left. Our finding was chiasmatic syndrome with more significant impairment on the left side. Subsequent magnetic resonance imaging (MRI) was suspicious for Rathke's cleft cyst (RCC). A neurosurgical intervention was performed the week following MRI . Using a subfrontal approach via a small right frontal craniotomy, the tumor was released from surrounding neural structures and radically removed using microsurgical techniques. During the procedure, it was not completely clear whether it was RCC or a craniopharyngioma; the biopsy findings were consistent with RCC with xanthogranulomatous changes. The authors emphasize the importance of visual field examination in unclear visual disorders, as well as the importance of follow-up examinations to uncover recurrences.
本文报告了一例70岁女性患者,该患者既往无任何眼部疾病史。发现在另一家诊所进行眼科检查前2周,有“东西掉进”她的右眼;她注意到左眼视力下降。眼科检查显示,右眼视力(VARE)为0.4,左眼视力(VALE):1米处指数。双眼早期白内障,右眼更明显。视神经(ON)评估显示,视乳头杯盘比(C/D)分别为右眼0.6、左眼0.7。首次检查后1个月,发现VARE为0.4,VALE为0.16。白内障程度与视力下降不相符。发现右侧视乳头有凹陷(C/D = 0.6),左侧视乳头萎缩(C/D = 0.7)。除此之外,眼底评估正常。右眼视野(VF)上象限颞侧不完全性偏盲,左眼VF颞侧偏盲并延伸至中央部分。电生理检查(图形视觉诱发电位)显示右侧振幅明显降低,P100潜伏期无延长;左侧观察到无反应。我们的发现为交叉综合征,左侧损害更显著。随后的磁共振成像(MRI)怀疑为拉克氏裂囊肿(RCC)。MRI检查后一周进行了神经外科手术干预。通过右侧额部小颅骨切开术采用额下入路,将肿瘤从周围神经结构中分离出来,并使用显微外科技术彻底切除。在手术过程中,尚不完全清楚它是RCC还是颅咽管瘤;活检结果与伴有黄色肉芽肿性改变的RCC一致。作者强调视野检查在不明原因视力障碍中的重要性,以及随访检查以发现复发的重要性。