Han Yue
Department of Neonatology, Maternal and Child Health Hospital of Hubei Province, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430070, China.
Zhongguo Dang Dai Er Ke Za Zhi. 2025 Apr 15;27(4):487-492. doi: 10.7499/j.issn.1008-8830.2409146.
The primary source of blood transfusions for neonates is allogeneic adult blood. While allogeneic adult blood can provide timely and effective transfusion support for neonates, there are differences in hemoglobin types and coagulation systems between adults and neonates, along with potential infection risks. In recent years, the clinical value of cord blood transfusion in early surgical interventions and anemia management for neonates has been increasingly recognized. Studies have shown that cord blood transfusion not only reduces the incidence of complications in preterm infants but also provides a safer alternative transfusion source for neonates. However, cord blood transfusion has not yet been widely adopted. This article reviews the advantages, clinical application progress, and significance of cord blood transfusion in neonates, to provide evidence supporting its broader clinical implementation.
新生儿输血的主要来源是异体成人血液。虽然异体成人血液可为新生儿提供及时有效的输血支持,但成人与新生儿在血红蛋白类型和凝血系统方面存在差异,同时还存在潜在的感染风险。近年来,脐血输血在新生儿早期手术干预和贫血管理中的临床价值日益得到认可。研究表明,脐血输血不仅降低了早产儿并发症的发生率,还为新生儿提供了更安全的替代输血来源。然而,脐血输血尚未得到广泛应用。本文综述了脐血输血在新生儿中的优势、临床应用进展及意义,为其更广泛的临床应用提供依据。