Abella Mireia, García-Mollá Adrián, Sanz Aitana, Tomás José M, Aliño Marta
Department of Methodology of Behavioral Sciences, University of Valencia, Valencia, Spain.
Faculty of Health Sciences, Valencian International University, Research Group in Psychology and Quality of Life (PsiCal), Valencia, Spain.
Aging Ment Health. 2025 Jul;29(7):1266-1273. doi: 10.1080/13607863.2025.2478502. Epub 2025 Apr 17.
We aimed to study the longitudinal relationship between immediate memory, depressive symptomatology and loneliness controlling for age and number of chronic diseases over time.
The study sample consisted of 64,887 participants from three consecutive waves of the Survey of Health, Ageing and Retirement in Europe project, aged 50 or older at the first time ( = 66.68, SD = 10.034). We used cross-lagged panel model.
Within each temporal moment, associations between immediate memory and depressive symptomatology, and associations between immediate memory and loneliness were negative. Associations between depressive symptomatology and loneliness were positive. These three variables feedback on each other over time through small and medium effects. Immediate memory is more affected by depressive symptomatology than by loneliness. However, loneliness may exert a greater negative effect, in relative terms, on immediate memory when it coexists with depressive symptomatology. Depressive symptomatology is more affected by loneliness than by immediate memory deficits. However, deficits in immediate memory may affect depressive symptomatology more in relative terms because such deficits are exacerbated by elevated scores of depressive symptomatology.
Despite the effect sizes being small to medium, depressive symptomatology and loneliness are risk factors for cognitive functioning. In addition, cognitive impairment aggravates depressive symptoms and loneliness feelings.
我们旨在研究即时记忆、抑郁症状和孤独感之间随时间变化的纵向关系,并控制年龄和慢性病数量。
研究样本包括来自欧洲健康、老龄化和退休调查项目连续三波的64887名参与者,首次参与时年龄在50岁及以上(平均年龄=66.68,标准差=10.034)。我们使用了交叉滞后面板模型。
在每个时间点,即时记忆与抑郁症状之间以及即时记忆与孤独感之间的关联均为负相关。抑郁症状与孤独感之间的关联为正相关。随着时间的推移,这三个变量通过中小效应相互反馈。即时记忆受抑郁症状的影响大于受孤独感的影响。然而,孤独感与抑郁症状共存时,相对而言可能对即时记忆产生更大的负面影响。抑郁症状受孤独感的影响大于受即时记忆缺陷的影响。然而,即时记忆缺陷相对而言可能对抑郁症状影响更大,因为此类缺陷会因抑郁症状得分升高而加剧。
尽管效应大小为中小程度,但抑郁症状和孤独感是认知功能的危险因素。此外,认知障碍会加重抑郁症状和孤独感。