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[法属圭亚那的疟疾控制：2024年这个法国最后一个疟疾流行地区面临哪些挑战？]

[Malaria control in French Guiana: What are the challenges in this last endemic French territory in 2024?].

作者信息

Dahuron Laureen, Musset Lise, Tréhard Hélène, Sanna Alice, Dia Aïssata, Lazrek Yassamine, Naldjinan-Kodbaye Richard, Cébrian Virginie, Carvalho Luisiane, Andro Yannick, Bonot Bérengère, Boutrou Mathilde, Lesens Olivier, Turnier Paul Le, Abboud Philippe, Daverton Brice, Mubenga Francky, Oberlis Margot, Duchemin Jean-Bernard, Djossou Félix, Patarot Delphine, Rwagitinywa Joseph, Mosnier Émilie, Douine Maylis, Epelboin Loïc

机构信息

Unité de maladies infectieuses et tropicales (UMIT), Centre hospitalier de Cayenne (CHC), Guyane, France.

Centre national de référence du paludisme, Laboratoire de parasitologie, Centre collaborateur OMS pour la surveillance des résistances aux antipaludiques, Cayenne, France.

出版信息

Med Trop Sante Int. 2025 Mar 20;5(1). doi: 10.48327/mtsi.v5i1.2025.536. eCollection 2025 Mar 31.

DOI:10.48327/mtsi.v5i1.2025.536
PMID:40248577
原文链接:
https://pmc.ncbi.nlm.nih.gov/articles/PMC12001996/
Abstract

French Guiana, the last malaria-endemic region of France, is facing an epidemic resurgence of malaria since the end of 2023. This epidemic, primarily caused by , mainly affects populations that are far from the healthcare system. It has highlighted the difficulties of providing a full course of treatment. This includes both curative treatment with artemisinin derivatives (following the withdrawal of chloroquine from the market) and eradicative treatment with primaquine, with the challenge of excluding G6PD deficiency. The aim of this paper is to describe the problems of malaria diagnosis and management in this unique territory, to highlight the adaptations made and to propose diagnostic, therapeutic and follow-up schemes adapted to the possibilities of access to the health system, with a view to homogenizing practices. This article also highlights the innovative strategies implemented in French Guiana to deal with this new epidemic: health mediation, mobile malaria team, rapid diagnostic tests and immediate out-of-hospital treatment Test and Treat, development of self-diagnosis and self-treatment. These proposals are part of a campaign to eliminate malaria in France in the short term.

摘要

法属圭亚那是法国最后一个疟疾流行地区，自2023年底以来正面临疟疾疫情的再度爆发。这场疫情主要由[未提及具体原因]引起，主要影响远离医疗系统的人群。它凸显了提供完整疗程治疗的困难。这包括使用青蒿素衍生物进行治疗（自氯喹退市后）以及使用伯氨喹进行根治性治疗，同时面临排除葡萄糖-6-磷酸脱氢酶（G6PD）缺乏症的挑战。本文旨在描述这个独特地区疟疾诊断和管理的问题，强调所做的调整，并提出适应卫生系统可及性的诊断、治疗和随访方案，以期实现实践的同质化。本文还强调了法属圭亚那为应对这一新疫情而实施的创新策略：健康调解、流动疟疾防治小组、快速诊断检测以及院外即时治疗“检测与治疗”、自我诊断和自我治疗的发展。这些提议是法国短期内消除疟疾运动的一部分。

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