McLaughlin S, Speakman S, Johns J, McGuinness M, Swanson C, Muller L, Muwanga-Magoye T, Harmston C
Department of General Surgery, Whangarei Hospital, Te Whatu Ora Te Tai Tokerau, Whangarei, New Zealand.
Department of Surgery, University of Auckland, Auckland, New Zealand.
ANZ J Surg. 2025 Jun;95(6):1236-1241. doi: 10.1111/ans.70111. Epub 2025 Apr 18.
Increasing rates of opioid prescribing are a growing concern due to associations with dependency and misuse. Management of pain in trauma is important, but represents an under-investigated opioid initiation event. This study aimed to analyze opioid prescription patterns at discharge in trauma patients within a provincial setting in Aotearoa New Zealand.
To address this aim, a cohort of 500 trauma patients aged 18-64 years, admitted to Tauranga or Whakatāne Hospital between 21 April 2017 and 31 December 2017, were retrospectively assessed. Data were sourced from the Midland Trauma Registry (MTR), which captures patients admitted to hospital within 7 days of injury. Opioid prescriptions at discharge and repeat prescriptions up to 12 months post-discharge were assessed, with doses standardized using Morphine Milligram Equivalents (MMEs).
Of the 473 opioid-naïve patients identified, 69.1% were prescribed opioids at discharge. A higher Injury Severity Score (ISS) was associated with increased opioid prescribing at discharge and a higher likelihood of repeated opioid prescriptions after discharge. Within 3 months, 36.1% of patients received repeat prescriptions, decreasing to 13.5% between 3 and 6 months and 7.3% between 6 and 12 months.
This is the first reported study assessing opioid prescribing after trauma in Aotearoa New Zealand and found that a higher ISS was associated with increased opioids prescribed at discharge and a greater risk of repeat prescriptions. These findings highlight the importance of education and prescribing protocols to balance pain management with the risk of long-term use.
由于与药物依赖和滥用相关,阿片类药物处方率的不断上升日益受到关注。创伤疼痛的管理很重要,但这是一个研究不足的阿片类药物起始事件。本研究旨在分析新西兰奥特亚罗瓦一个省级地区创伤患者出院时的阿片类药物处方模式。
为实现这一目标,对2017年4月21日至2017年12月31日期间入住陶朗加或瓦卡塔尼医院的500名18 - 64岁创伤患者进行了回顾性评估。数据来源于中部地区创伤登记处(MTR),该登记处记录受伤后7天内入院的患者。评估了出院时的阿片类药物处方以及出院后长达12个月的重复处方,剂量使用吗啡毫克当量(MME)进行标准化。
在473名初次使用阿片类药物的患者中,69.1%在出院时被开具了阿片类药物。较高的损伤严重度评分(ISS)与出院时阿片类药物处方增加以及出院后重复开具阿片类药物的可能性增加相关。在3个月内,36.1%的患者接受了重复处方,在3至6个月之间降至13.5%,在6至12个月之间降至7.3%。
这是新西兰奥特亚罗瓦首次报道的评估创伤后阿片类药物处方的研究,发现较高的ISS与出院时开具的阿片类药物增加以及重复处方的更大风险相关。这些发现凸显了教育和处方协议在平衡疼痛管理与长期使用风险方面的重要性。