Benchanna Rachid, Kaakoua Mohamed, Azami Mohamed Amine, Bellasri Salah, Janah Hicham, Kherrab Anas, Sassi Soufiane, Benjelloune Amine
Department of Pulmonology, Avicenne Military Hospital, Marrakech, MAR.
Department of Medical Oncology, Avicenne Military Hospital, Marrakech, MAR.
Cureus. 2025 Mar 21;17(3):e80947. doi: 10.7759/cureus.80947. eCollection 2025 Mar.
Misleading presentations of lepidic adenocarcinomas (ADC) often lead to diagnostic delays, potentially reducing the chances of curative treatment. We report a case of mucinous lepidic ADC that mimicked pulmonary tuberculosis and was diagnosed at a late stage. The tumor showed no epidermal growth factor receptor (EGFR) expression or anaplastic lymphoma kinase (ALK) rearrangement and was characterized by bilateral pulmonary involvement without distant metastases. Through this case, the authors emphasize the need to consider lepidic ADC in cases of chronic pulmonary consolidation, despite atypical radio-clinical presentations that may be encountered in routine practice.
鳞屑状腺癌(ADC)的误导性表现常常导致诊断延误,可能会降低治愈性治疗的机会。我们报告一例黏液性鳞屑状ADC病例,该病例酷似肺结核,且在晚期才得以诊断。肿瘤未显示表皮生长因子受体(EGFR)表达或间变性淋巴瘤激酶(ALK)重排,其特征为双侧肺受累且无远处转移。通过该病例,作者强调,尽管在常规实践中可能会遇到非典型的放射学-临床特征,但对于慢性肺实变病例,仍需考虑鳞屑状ADC的可能性。