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一例系统性红斑狼疮合并继发性伊文氏综合征病例。

A Case of Systemic Lupus Erythematosus Complicated by Secondary Evans Syndrome.

作者信息

Drallmeier Madison, Grossmann Meghan, Haftka-George Alexis

机构信息

Internal Medicine, Henry Ford Health System, Detroit, USA.

Internal Medicine, Wayne State University, Detroit Medical Center, Detroit, USA.

出版信息

Cureus. 2025 Mar 21;17(3):e80959. doi: 10.7759/cureus.80959. eCollection 2025 Mar.

Abstract

Evans syndrome (ES) is a condition that describes the development of multiple cytopenias, including autoimmune hemolytic anemia (AIHA), immune thrombocytopenia (ITP), and autoimmune neutropenia (AIN). ES can be idiopathic or caused by an underlying condition, known as secondary ES. While secondary ES is associated with increased morbidity and mortality, any diagnosis of ES confers a poor prognosis. In this case report, we describe a young male patient diagnosed with systemic lupus erythematosus (SLE) and secondary ES that was complicated by multiple relapses and subsequent infections, bleeding events, and thrombotic events that ultimately led to the passing of the patient.

摘要

伊文斯综合征(ES)是一种描述多种血细胞减少症发展情况的病症,包括自身免疫性溶血性贫血(AIHA)、免疫性血小板减少症(ITP)和自身免疫性中性粒细胞减少症(AIN)。ES可以是特发性的,也可由潜在病症引起,后者称为继发性ES。虽然继发性ES与发病率和死亡率增加相关,但任何ES诊断都预示着预后不良。在本病例报告中,我们描述了一名年轻男性患者,他被诊断患有系统性红斑狼疮(SLE)和继发性ES,该病症并发多次复发以及随后的感染、出血事件和血栓形成事件,最终导致患者死亡。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/79be/12009602/57a4ba81a06e/cureus-0017-00000080959-i01.jpg

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