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基于游戏的干预措施对自闭症谱系障碍儿童和青少年的影响:一项系统评价与荟萃分析。

The effect of game-based interventions on children and adolescents with autism spectrum disorder: A systematic review and meta-analysis.

作者信息

Gao Jiaxin, Song Wei, Huang Dunbing, Zhang Anren, Ke Xiaohua

机构信息

School of Health and Rehabilitation, Chengdu University of Traditional Chinese Medicine, Chengdu, China.

Department of Rehabilitation Medicine, Shanghai Fourth People's Hospital Affiliated to Tongji University, Shanghai, China.

出版信息

Front Pediatr. 2025 Apr 4;13:1498563. doi: 10.3389/fped.2025.1498563. eCollection 2025.

Abstract

PURPOSE

The purpose of this meta-analysis was to conduct a comprehensive evaluation of randomized controlled trials (RCTs) of game-based interventions (GBI) for children and adolescents with autism spectrum disorder (ASD) to identify the clinical efficacy of GBI on core symptoms and other concomitant symptoms of ASD.

METHODS

PubMed, Web of Science, Embase and the Cochrane Library were systematically searched for articles published until July 2023.

RESULTS

Twenty-four studies with 1,801 patients met the inclusion criteria. The results showed that GBI had a significant positive effect on social skills ( = -0.59,  = 0.004), social behaviors ( = 0.45,  < 0.001), and cognition ( = 0.57,  < 0.001) in children and adolescents with ASD, while the effects of language expression ( = 0.15), anxiety ( = -0.13), and parenting stress ( = -0.51) were small and nonsignificant.

CONCLUSIONS

The results of the current meta-analysis showed that GBI was effective in improving social skills, social behaviors and cognition in children and adolescents with ASD in the existing studies and was not significant in improving language skills, anxiety and parental stress, but due to the limited number and low quality of the included studies, the above conclusions need to be validated by conducting more large-sample, high-quality RCTs.

SYSTEMATIC REVIEW REGISTRATION

www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42023390793, identifier: CRD42023390793.

摘要

目的

本荟萃分析旨在对针对自闭症谱系障碍(ASD)儿童和青少年的基于游戏的干预措施(GBI)的随机对照试验(RCT)进行全面评估,以确定GBI对ASD核心症状和其他伴随症状的临床疗效。

方法

系统检索了PubMed、科学网、Embase和Cochrane图书馆中截至2023年7月发表的文章。

结果

24项研究共1801例患者符合纳入标准。结果显示,GBI对ASD儿童和青少年的社交技能(= -0.59, = 0.004)、社交行为(= 0.45, < 0.001)和认知(= 0.57, < 0.001)有显著积极影响,而对语言表达(= 0.15)、焦虑(= -0.13)和养育压力(= -0.51)的影响较小且无统计学意义。

结论

当前荟萃分析结果表明,在现有研究中GBI对改善ASD儿童和青少年的社交技能、社交行为和认知有效,在改善语言技能、焦虑和父母压力方面不显著,但由于纳入研究数量有限且质量较低,上述结论需要通过开展更多大样本、高质量的RCT进行验证。

系统评价注册

www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42023390793,标识符:CRD4202339

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e481/12006128/36c5a91849d6/fped-13-1498563-g001.jpg

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