肺高血压与心房颤动患者左心耳封堵术后的结局：一项基于人群的分析。
Pulmonary hypertension and outcomes following left atrial appendage occlusion device placement for atrial fibrillation: A population-based analysis.
作者信息
Abdallah Nadhem, Alsayed Momen
机构信息
Department of Internal Medicine Hennepin Healthcare Minneapolis Minnesota USA.
Banner University Medical Center University of Arizona Tucson Arizona USA.
出版信息
J Arrhythm. 2025 Apr 20;41(2):e70071. doi: 10.1002/joa3.70071. eCollection 2025 Apr.
BACKGROUND
Pulmonary hypertension (PH) is linked to poor outcomes in cardiac procedures, but data on left atrial appendage occlusion device (LAAOD) placement are limited.
METHODS
Using the 2016-2020 Nationwide Readmission Database, we compared in-hospital outcomes between AF patients with and without PH.
RESULTS
Among 48,692 AF-LAAOD patients, 5.9% had PH. PH was associated with higher mortality, prolonged ventilation, AKI, vasopressor use, interatrial septum repair, LOS, and costs. No differences were found in the odds of readmissions, major bleeding events, vascular complications, stroke, or cardiac arrest.
CONCLUSION
PH in AF-LAAOD patients is associated with higher fatal and nonfatal adverse outcomes.
背景
肺动脉高压（PH）与心脏手术的不良预后相关，但左心耳封堵装置（LAAOD）植入的数据有限。
方法
利用2016 - 2020年全国再入院数据库，我们比较了有和没有PH的房颤患者的住院结局。
结果
在48,692例接受LAAOD治疗的房颤患者中，5.9%患有PH。PH与更高的死亡率、通气时间延长、急性肾损伤、血管活性药物使用、房间隔修复、住院时间和费用相关。在再入院几率、大出血事件、血管并发症、中风或心脏骤停方面未发现差异。
结论
接受LAAOD治疗的房颤患者中的PH与更高的致命和非致命不良结局相关。
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