Won Sookyung, Kim Hyeon Ji, Park Jee Yoon, Oh Kyung Joon, Choi Sung Hee, Jang Hak Chul, Moon Joon Ho
Division of Endocrinology and Metabolism, Department of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea.
Department of Obstetrics and Gynecology, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea.
J Korean Med Sci. 2025 Apr 21;40(15):e46. doi: 10.3346/jkms.2025.40.e46.
To assess the quality of life (QoL) and treatment satisfaction with intermittently-scanned continuous glucose monitoring (isCGM) in women with gestational diabetes mellitus (GDM).
This prospective observational study included 189 women with GDM who completed the Korean version of the Audit of Diabetes-Dependent Quality of Life Questionnaire (K-ADDQoL). Among them, 25 women who utilized isCGM between gestational weeks 30 and 34 completed the Korean version of the Diabetes Treatment Satisfaction Questionnaire change version (K-DTSQc) to evaluate their satisfaction with isCGM during pregnancy.
GDM had a negative impact on the perceived QoL in 89.4% of the women. All 19 domains of the K-ADDQoL were adversely influenced by GDM, with the most significant impact on the freedom to eat (weighted impact score, -6.98 ± 2.49, < 0.001) and the least impact on the sex life (-0.25 ± 0.80, = 0.008). Younger women and those treated with insulin perceived themselves as being more affected in their QoL due to GDM. Women perceived to have less effect on their QoL attributed to GDM exhibited higher ΔHbA1c one year after delivery (ΔHbA1c, 0.3 ± 0.4% vs. 0.0 ± 0.4% in less affected vs. more affected women). The utilization of isCGM improved treatment satisfaction (overall satisfaction score, 10.36 ± 9.21, < 0.001), independent of glycemic control during pregnancy.
Although GDM negatively affects the perceived QoL during pregnancy, attentiveness to GDM management may have a positive impact on long-term glycemic control. Moreover, employing isCGM can enhance treatment satisfaction in women with GDM.
评估间歇性扫描连续血糖监测(isCGM)对妊娠期糖尿病(GDM)女性生活质量(QoL)和治疗满意度的影响。
这项前瞻性观察性研究纳入了189名完成韩国版糖尿病相关生活质量调查问卷(K-ADDQoL)的GDM女性。其中,25名在妊娠30至34周期间使用isCGM的女性完成了韩国版糖尿病治疗满意度调查问卷变化版(K-DTSQc),以评估她们在孕期对isCGM的满意度。
89.4%的女性中,GDM对其感知到的生活质量有负面影响。K-ADDQoL的所有19个领域均受到GDM的不利影响,对饮食自由的影响最为显著(加权影响得分,-6.98±2.49,<0.001),对性生活的影响最小(-0.25±0.80,=0.008)。年轻女性和接受胰岛素治疗的女性认为自己的生活质量受GDM的影响更大。认为GDM对其生活质量影响较小的女性在产后一年的糖化血红蛋白变化值(ΔHbA1c)更高(ΔHbA1c,受影响较小的女性为0.3±0.4%,受影响较大的女性为0.0±0.4%)。使用isCGM可提高治疗满意度(总体满意度得分,10.36±9.21,<0.001),与孕期血糖控制无关。
尽管GDM对孕期感知到的生活质量有负面影响,但对GDM管理的关注可能对长期血糖控制有积极影响。此外,采用isCGM可提高GDM女性的治疗满意度。