Rendon Adrian, Luhning Susana, Bardin Philip, Celis-Preciado Carlos Andrés, El Shazly Moustafa, Cohen-Todd Mark, Ismail Ahmad Izuanuddin, Idrees Majdy, Lim Seong Yong, Fu Pin-Kuei, Seemungal Terence, Köktürk Nurdan, Hurst John R
Universidad Autónoma de Nuevo León, Hospital Universitario "Dr. José Eleuterio González", Centro de Investigación, Prevención y Tratamiento de Infecciones Respiratorias (CIPTIR), Monterrey, México.
Pneumologist, Hospital Nacional de Clínicas, Universidad Nacional de Córdoba, Córdoba, Argentina.
Int J Chron Obstruct Pulmon Dis. 2025 Apr 16;20:1111-1129. doi: 10.2147/COPD.S502971. eCollection 2025.
Exacerbations of chronic obstructive pulmonary disease (COPD) continue to place a considerable disease and financial burden on both patients and healthcare systems, particularly in low- and middle-income countries (LMICs). Therefore, preventing future exacerbations remains a key treatment goal. However, gaps remain in the standard of COPD care following exacerbations, despite the availability of evidence-based recommendations providing guidance on discharging patients from hospital or emergency department (ED) after a COPD exacerbation. To better understand these gaps in clinical practice, an advisory board meeting of 13 international pulmonologists was convened in September 2022, with the principal objective to formulate and recommend an evidence-based hospital discharge protocol following a COPD exacerbation, with a particular focus on LMICs. Based on identified gaps in COPD care, recommendations for alleviating the burden of exacerbations were proposed, which could be delivered as a discharge protocol for implementation in hospitals and/or ED. Following a review of the available clinical evidence, including an online survey of 11 pre-meeting questions and 5 additional questions discussed during the meeting, the key unmet needs identified by the experts included poor integration of standardized protocols in routine clinical practice, failure to ensure consistent delivery of post-discharge care, and lack of efficiently functioning healthcare systems. A protocol was formulated for delivery as part of a disease management program involving an interdisciplinary approach and a care bundle, aiming to address gaps in discharge-related care by determining the likelihood of readmission and optimizing maintenance treatment plans based on assessment of symptoms and future exacerbation risk. This can provide holistic care following hospital/ED discharge and personalized treatment plans by advocating referral to a specialist. To ensure wide-ranging uptake, implementation of a discharge protocol will need to be tailored to local healthcare settings by conducting feasibility studies, standardizing clinical pathways and healthcare policies, and engaging relevant stakeholders.
慢性阻塞性肺疾病(COPD)的急性加重继续给患者和医疗系统带来巨大的疾病负担和经济负担,在低收入和中等收入国家(LMICs)尤其如此。因此,预防未来的急性加重仍然是一个关键的治疗目标。然而,尽管有基于证据的建议为COPD急性加重后患者出院或从急诊科(ED)出院提供指导,但急性加重后COPD护理的标准仍存在差距。为了更好地了解这些临床实践中的差距,2022年9月召开了一次由13名国际肺病专家组成的咨询委员会会议,主要目的是制定并推荐一份基于证据的COPD急性加重后医院出院方案,特别关注低收入和中等收入国家。基于在COPD护理中发现的差距,提出了减轻急性加重负担的建议,这些建议可以作为出院方案在医院和/或急诊科实施。在审查了现有临床证据后,包括对会前11个问题和会议期间讨论的另外5个问题的在线调查,专家们确定的关键未满足需求包括标准化方案在常规临床实践中的整合不佳、未能确保出院后护理的持续提供以及缺乏高效运作的医疗系统。制定了一项方案,作为疾病管理计划的一部分实施,该计划采用跨学科方法和护理包,旨在通过确定再入院的可能性并根据症状评估和未来急性加重风险优化维持治疗计划来解决出院相关护理中的差距。这可以在医院/急诊科出院后提供全面护理,并通过倡导转诊至专科医生提供个性化治疗计划。为确保广泛采用,需要通过开展可行性研究、标准化临床路径和医疗政策以及让相关利益攸关方参与,使出院方案的实施适合当地医疗环境。