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经腹途径腹腔镜膀胱顶部输尿管再植术治疗原发性梗阻性巨输尿管

Transabdominal approach laparoscopic ureteral reimplantation at the top of the bladder for the treatment of primary obstructive megaureter.

作者信息

Shang Xianhui, Luo Zhen, Li Yingbo, Zhou Guangxu, Mao Yuchen, Tan Hongyang, Mao Kaiyi, Zhao Peng, Wang Cao, Jin Zhu, Liu Yuanmei

机构信息

Department of Pediatric Surgery, Affiliated Hospital of Zunyi Medical University, Zunyi, China.

Department of Pediatric Surgery, Guizhou Children's Hospital, Zunyi, China.

出版信息

Front Pediatr. 2025 Apr 7;13:1552433. doi: 10.3389/fped.2025.1552433. eCollection 2025.

Abstract

BACKGROUND

Congenital primary obstructive megaureter (POM) is characterized by distal ureteral obstruction, leading to ureteral dilation, hydronephrosis, and potential renal impairment. Surgical intervention is necessary for severe hydronephrosis (SFU grade III-IV) or progressive renal decline. Open ureteral reimplantation is the standard treatment but is associated with significant surgical trauma and prolonged recovery. This study evaluates the safety and efficacy of transabdominal laparoscopic ureteral reimplantation (TALUR) at the posterior wall-bladder dome and compares its outcomes with the Politano procedure.

METHODS

This retrospective, single-center study included pediatric POM patients who underwent ureteral reimplantation at the Affiliated Hospital of Zunyi Medical University from October 2019 to December 2023. Patients were assigned to the TALUR group ( = 21) or the Politano group ( = 20). Preoperative imaging, including renal ultrasound, magnetic resonance urography (MRU), and voiding cystourethrography (VCUG), confirmed the diagnosis. Primary endpoints included postoperative distal ureteral diameter, renal pelvic diameter, surgical success rate, perioperative complications, hospital stay, and vesicoureteral reflux (VUR) incidence. Follow-up assessments included ultrasound, MRU, and VCUG.

RESULTS

All procedures were successfully completed without conversion to open surgery. The TALUR group had a significantly shorter operative time (76.5 ± 12.6 min) compared to the Politano group (95.7 ± 14.8 min,  < 0.05). Postoperatively, distal ureteral diameter decreased from 14.6 ± 3.7 mm-4.8 ± 2.1 mm ( < 0.05), and renal pelvic dilation improved from 24.7 ± 5.3 mm-12.3 ± 2.6 mm ( < 0.05). The TALUR group had a shorter hospital stay (4.5 ± 0.5 vs. 6.1 ± 0.7 days,  < 0.05). Follow-up MRU showed improved ureteral patency and resolution of hydronephrosis. VCUG at six months showed mild VUR in two TALUR patients (9.5%) and one Politano patient (5.0%), all resolving within one year.

CONCLUSION

TALUR is a safe and effective minimally invasive technique for pediatric POM. Compared to the Politano procedure, TALUR offers shorter operative time, faster recovery, and comparable efficacy. Further large-scale studies are required to confirm its long-term effectiveness.

摘要

背景

先天性原发性梗阻性巨输尿管(POM)的特征是输尿管远端梗阻,导致输尿管扩张、肾积水以及潜在的肾功能损害。对于重度肾积水(SFU分级III-IV级)或进行性肾功能减退,手术干预是必要的。开放性输尿管再植术是标准治疗方法,但会带来显著的手术创伤和较长的恢复时间。本研究评估经腹腹腔镜输尿管膀胱后壁-膀胱顶部再植术(TALUR)的安全性和有效性,并将其结果与波利塔诺手术进行比较。

方法

这项回顾性单中心研究纳入了2019年10月至2023年12月在遵义医科大学附属医院接受输尿管再植术的小儿POM患者。患者被分为TALUR组(n = 21)或波利塔诺组(n = 20)。术前影像学检查,包括肾脏超声、磁共振尿路造影(MRU)和排尿性膀胱尿道造影(VCUG),确诊病情。主要终点包括术后输尿管远端直径、肾盂直径、手术成功率、围手术期并发症、住院时间以及膀胱输尿管反流(VUR)发生率。随访评估包括超声、MRU和VCUG。

结果

所有手术均成功完成,无需转为开放手术。与波利塔诺组(95.7 ± 14.8分钟)相比,TALUR组的手术时间显著更短(76.5 ± 12.6分钟,P < 0.05)。术后,输尿管远端直径从14.6 ± 3.7毫米降至4.8 ± 2.1毫米(P < 0.05),肾盂扩张从24.7 ± 5.3毫米改善至12.3 ± 2.6毫米(P < 0.05)。TALUR组的住院时间更短(4.5 ± 0.5天对6.1 ± 0.7天,P < 0.05)。随访MRU显示输尿管通畅性改善,肾积水消退。六个月时的VCUG显示,两名TALUR患者(9.5%)和一名波利塔诺患者(5.0%)出现轻度VUR,均在一年内消退。

结论

TALUR是一种用于小儿POM的安全有效的微创技术。与波利塔诺手术相比,TALUR手术时间更短、恢复更快且疗效相当。需要进一步的大规模研究来证实其长期有效性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f1f/12009922/d8fc80737127/fped-13-1552433-g001.jpg

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