Wang K P, Britt E J, Haponik E F, Fishman E K, Siegelman S S, Erozan Y S
Ann Otol Rhinol Laryngol. 1985 Jul-Aug;94(4 Pt 1):382-5.
Transbronchial needle aspiration of cytopathological specimens has proven useful in the diagnosis and staging of bronchogenic carcinoma, but its value in conditions requiring histologic confirmation has been hampered by the small size of the sample provided. To expand the utility of this procedure, we designed a larger (18 gauge) needle with a beveled stylet with which tissue cores for histologic study can be obtained during rigid bronchoscopy, and we have evaluated the safety and efficacy of this technique. Diagnoses of five neoplastic and three granulomatous diseases were established in eight of the ten patients with this procedure, and there were no complications. These findings suggest that transbronchial needle aspiration biopsy is relatively safe and effective, further extending the bronchoscopic approach to selected patients with mediastinal disease.
经支气管针吸获取细胞病理学标本已被证明在支气管源性癌的诊断和分期中有用，但在需要组织学确诊的情况下，其价值因所提供样本量小而受到限制。为扩大该操作的效用，我们设计了一种更大（18号）的带有斜面针芯的针，通过它可在硬质支气管镜检查期间获取用于组织学研究的组织芯，并且我们评估了该技术的安全性和有效性。该操作在10例患者中的8例确诊了5种肿瘤性疾病和3种肉芽肿性疾病，且无并发症。这些发现表明经支气管针吸活检相对安全有效，进一步将支气管镜检查方法扩展至部分患有纵隔疾病的患者。
