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多服了54片药:氨氯地平和氯沙坦过量一例报告

Fifty-Four Tablets Too Many: A Case Report of Amlodipine and Losartan Overdose.

作者信息

Uprety Nishan, Bhandari Bishal, Dhungana Vinayak, Neupane Sulav, Neupane Sunischit Chandra, Tamang Sujan, Acharya Samiksha

机构信息

Nepalese Army Institute of Health Sciences Kathmandu Nepal.

BP Koirala Memorial Cancer Hospital Bharatpur Chitwan Nepal.

出版信息

Clin Case Rep. 2025 Apr 22;13(4):e70457. doi: 10.1002/ccr3.70457. eCollection 2025 Apr.

Abstract

Overdoses of widely used cardiovascular drugs calcium channel blockers and angiotensin receptor blockers cause severe hemodynamic instability. Timely management with hyperinsulinemia-euglycemia therapy, vasopressors, and calcium gluconate is critical. Enhanced clinical vigilance, prompt intervention, and long-term care, including psychological evaluation, are essential to address underlying factors and prevent recurrence of overdoses.

摘要

广泛使用的心血管药物钙通道阻滞剂和血管紧张素受体阻滞剂过量会导致严重的血流动力学不稳定。采用高胰岛素血症-正常血糖疗法、血管升压药和葡萄糖酸钙进行及时处理至关重要。提高临床警惕性、及时干预以及包括心理评估在内的长期护理对于解决潜在因素和预防过量用药复发至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c015/12014512/97cdae50a119/CCR3-13-e70457-g001.jpg

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