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肿瘤治疗中微波消融的进展及未来方向。

Advancements in microwave ablation for tumor treatment and future directions.

作者信息

Dong Fangying, Wu Yijie, Li Weiwei, Li Xiaoping, Zhou Jing, Wang Bin, Chen Minjie

机构信息

Emergency Department, the Second Affiliated Hospital of Jiaxing University, Jiaxing, Zhejiang, China.

General Practice, Taozhuang Branch of the First People's Hospital of Jiashan, Jiaxing, Zhejiang, China.

出版信息

iScience. 2025 Mar 7;28(4):112175. doi: 10.1016/j.isci.2025.112175. eCollection 2025 Apr 18.

Abstract

Microwave ablation (MWA) is a minimally invasive treatment that uses thermal energy to target and destroy tumors. Compared to other ablation methods, such as radiofrequency ablation (RFA), MWA operates at higher frequencies, allowing for faster ablation and larger treatment areas. In addition to its direct tumor-destroying effects, MWA has been shown to activate immune responses, contributing to long-term antitumor effects. MWA can also be combined with surgery, chemotherapy, and immunotherapy to enhance treatment outcomes. This review examines the current research on MWA's technical innovations, clinical applications, and its potential in improving cancer treatment efficacy.

摘要

微波消融(MWA)是一种微创治疗方法,它利用热能靶向并摧毁肿瘤。与其他消融方法(如射频消融(RFA))相比,MWA在更高的频率下运行,能够实现更快的消融速度和更大的治疗区域。除了直接的肿瘤破坏作用外,MWA还被证明可以激活免疫反应,从而产生长期的抗肿瘤效果。MWA还可以与手术、化疗和免疫疗法相结合,以提高治疗效果。本文综述了目前关于MWA的技术创新、临床应用及其在提高癌症治疗疗效方面潜力的研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/56ea/12017980/3863c4308d2b/fx1.jpg

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