产前和断奶前环境对青春期发育和精子生成的影响。

Prenatal and Preweaning Environmental Effects upon Pubertal Development and Sperm Production.

作者信息

Barth Albert, Perry Viv E A, Hamilton Lauren E, Sutovsky Peter, Oko Richard

机构信息

Department of Large Animal Clinical Sciences, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, SK, Canada.

Queensland Sperm Morphology Laboratory (QSML), Goondiwindi, QLD, Australia.

出版信息

Adv Anat Embryol Cell Biol. 2025;240:331-347. doi: 10.1007/978-3-031-70126-9_8.

DOI:10.1007/978-3-031-70126-9_8

PMID:40272593

Abstract

This chapter examines the role of early life perturbations upon the developing bull calf. Surprisingly, we observe effects upon sexual development and sperm quality, including sperm morphology, as early as the periconception period (-60 to 23 days post conception). Similarly, during postnatal life (prior to 6mths of age) dietary perturbations retard sexual development and sperm quality. Herein we discuss the ontology of development and examine why these periods of development are fundamental to fertility in the bull. Ultimately, this leads to recommendations for changes to current husbandry protocols.

摘要

本章探讨了生命早期干扰因素对发育中的公牛犊的影响。令人惊讶的是，我们早在受孕前后时期（受孕后-60至23天）就观察到了对性发育和精子质量的影响，包括精子形态。同样，在出生后生活中（6个月龄之前），饮食干扰会延缓性发育和精子质量。在此，我们讨论发育的本体论，并研究为什么这些发育阶段对公牛的生育能力至关重要。最终，这导致了对当前饲养方案变更的建议。