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脊髓损伤患者压疮的皮瓣重建:一项回顾性队列研究。

Flap reconstruction of pressure ulcers in patients with spinal cord injury: a retrospective cohort study.

作者信息

Mishra Ankit, Eldolify Mohammed, Shirley Rebecca, Chan James K-K

机构信息

Plastic Surgery and Burns Department, Stoke Mandeville Hospital, Buckinghamshire Healthcare NHS Trust, Aylesbury, UK.

Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK.

出版信息

Spinal Cord. 2025 Apr 25. doi: 10.1038/s41393-025-01080-2.

Abstract

STUDY DESIGN

Retrospective case series.

OBJECTIVES

To describe our five-year experience of surgical excision and flap reconstruction of pressure ulcers in individuals with spinal cord injury (SCI).

SETTING

Tertiary spinal centre in Stoke Mandeville, United Kingdom.

METHODS

All spinal injury patients that underwent surgical reconstruction of pressure ulcers at the Stoke Mandeville Hospital National Spinal Injury Centre between 2018 and 2022 inclusive were included. Ulcers underwent 'pseudotumour' excision followed by either immediate or staged flap reconstruction. The primary outcome was complete healing at one year. Secondary outcomes included flap loss, complications, and return to theatre.

RESULTS

52 cases were included across 44 patients. 43 cases (82.7%) underwent immediate debridement and reconstruction. The mean number of procedures was 1.9 (range 1-6). Local flaps were used in 22 (41.5%) cases. There was one (1.9%) free flap (anterolateral thigh), eight (15.4%) pedicled flaps, and 21 (39.6%) flaps based on single perforators. 49 cases completed follow-up; 41 (83.7%) were healed at one year after their initial surgery. Immediate reconstructions were 36.7% more likely to achieve healing at this time point than staged cases (P = .028, Fisher's exact). There was partial or total flap loss in 15 (28.8%) cases. Thirty-nine complications were seen in 24 (46.2%) cases. Twenty-three cases (44.2%) required returns to theatre.

CONCLUSIONS

Surgical debridement with flap reconstruction is a safe and reliable treatment approach for pressure ulcers in those with SCI, with a complication rate comparable to existing literature. Immediate flap reconstruction and local flap designs may be associated with a lower risk of complications and higher healing rates.

摘要

研究设计

回顾性病例系列。

目的

描述我们在脊髓损伤(SCI)患者中进行压疮手术切除和皮瓣重建的五年经验。

地点

英国斯托克曼德维尔的三级脊髓中心。

方法

纳入2018年至2022年期间在斯托克曼德维尔医院国家脊髓损伤中心接受压疮手术重建的所有脊髓损伤患者。溃疡进行“假肿瘤”切除,然后立即或分期进行皮瓣重建。主要结局是术后一年完全愈合。次要结局包括皮瓣丢失、并发症和再次手术。

结果

44例患者共纳入52例病例。43例(82.7%)接受了立即清创和重建。平均手术次数为1.9次(范围1 - 6次)。22例(41.5%)使用局部皮瓣。有1例(1.9%)游离皮瓣(股前外侧),8例(15.4%)带蒂皮瓣,21例(39.6%)基于单一穿支的皮瓣。49例完成随访;41例(83.7%)在初次手术后一年愈合。在这一时间点,立即重建比分期重建愈合的可能性高36.7%(P = 0.028,Fisher精确检验)。15例(28.8%)出现部分或全部皮瓣丢失。24例(46.2%)出现39例并发症。23例(44.2%)需要再次手术。

结论

皮瓣重建手术清创是治疗SCI患者压疮的一种安全可靠的方法,并发症发生率与现有文献相当。立即皮瓣重建和局部皮瓣设计可能并发症风险较低且愈合率较高。

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