• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

新型冠状病毒肺炎相关的复视及其治疗

COVID-19-Related Diplopia and Its Treatment.

作者信息

Patricia Shannon, Kartika Antonia, Puspitasari Irma Melyani

机构信息

Bachelor Program in Pharmacy, Faculty of Pharmacy, Universitas Padjadjaran, Sumedang 45363, West Java, Indonesia.

National Eye Center Cicendo Eye Hospital, Bandung 40117, West Java, Indonesia.

出版信息

Medicina (Kaunas). 2025 Mar 28;61(4):626. doi: 10.3390/medicina61040626.

DOI:10.3390/medicina61040626
PMID:40282917
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12029126/
Abstract

: The effects of COVID-19 disease can manifest and cause eye complications, one of which is diplopia. Diplopia is a medical condition that makes one object appear like two images. People may also experience diplopia after receiving the COVID-19 vaccine, after contracting COVID-19, or following a COVID-19 infection. : This review aims to summarize the cases of COVID-19 that can cause diplopia and its treatment in the past 5 years. The literature search databases used for this review were PubMed and Scopus. The keywords used were "diplopia," "COVID-19," and "treatment." Sixteen articles were reviewed after screening and applying the inclusion criteria. : The results show that over the past 5 years, cases of diplopia related to COVID-19 have occurred in America, Europe, Asia, and Africa. Most studies are case reports, and the total number of patients was 26, with an age range of 14 to 81. : The diplopia cases recovered within 1 day to 8 months. Patients who experienced diplopia after receiving the COVID-19 vaccine, during COVID-19 infection, or after COVID-19 infection exhibited different symptoms. Nasopharyngeal swabs, magnetic resonance imaging (MRI), computerized tomography (CT) scans, visual acuity tests, slit lamp biomicroscope examinations, eye movement tests, funduscopic examinations, and blood tests were the most commonly performed tests. Corticosteroids such as prednisone, methylprednisolone, and prednisolone were the most commonly used drugs to treat diplopia. In addition to corticosteroids, antibiotics, antivirals, antiplatelets, and vitamins were also given. An eye patch was considered to alleviate the diplopia.

摘要

新冠病毒疾病的影响可能会显现并引发眼部并发症,其中之一就是复视。复视是一种病症,会使一个物体看起来像两个影像。人们在接种新冠疫苗后、感染新冠病毒期间或感染新冠病毒之后也可能会出现复视。

本综述旨在总结过去5年中可导致复视的新冠病例及其治疗方法。本综述使用的文献检索数据库为PubMed和Scopus。使用的关键词为“复视”“新冠病毒”和“治疗”。经过筛选并应用纳入标准后,共审查了16篇文章。

结果显示,在过去5年中,与新冠病毒相关的复视病例在美洲、欧洲、亚洲和非洲均有发生。大多数研究为病例报告,患者总数为26例,年龄范围在14岁至81岁之间。

复视病例在1天至8个月内康复。在接种新冠疫苗后、感染新冠病毒期间或感染新冠病毒之后出现复视的患者表现出不同症状。鼻咽拭子、磁共振成像(MRI)、计算机断层扫描(CT)、视力测试、裂隙灯显微镜检查、眼球运动测试、眼底检查和血液检查是最常进行的检查。泼尼松、甲泼尼龙和泼尼松龙等皮质类固醇是治疗复视最常用的药物。除皮质类固醇外,还使用了抗生素、抗病毒药物、抗血小板药物和维生素。眼罩被认为可缓解复视。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9321/12029126/1e0796d88836/medicina-61-00626-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9321/12029126/1e0796d88836/medicina-61-00626-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9321/12029126/1e0796d88836/medicina-61-00626-g001.jpg

相似文献

1
COVID-19-Related Diplopia and Its Treatment.新型冠状病毒肺炎相关的复视及其治疗
Medicina (Kaunas). 2025 Mar 28;61(4):626. doi: 10.3390/medicina61040626.
2
Folic acid supplementation and malaria susceptibility and severity among people taking antifolate antimalarial drugs in endemic areas.在流行地区,服用抗叶酸抗疟药物的人群中,叶酸补充剂与疟疾易感性和严重程度的关系。
Cochrane Database Syst Rev. 2022 Feb 1;2(2022):CD014217. doi: 10.1002/14651858.CD014217.
3
A randomized, double-blind, placebo-controlled phase III clinical trial to evaluate the efficacy and safety of SARS-CoV-2 vaccine (inactivated, Vero cell): a structured summary of a study protocol for a randomised controlled trial.一项评估 SARS-CoV-2 疫苗(灭活,Vero 细胞)有效性和安全性的随机、双盲、安慰剂对照 III 期临床试验:一项随机对照试验研究方案的结构化总结。
Trials. 2021 Apr 13;22(1):276. doi: 10.1186/s13063-021-05180-1.
4
Safety and Efficacy of Imatinib for Hospitalized Adults with COVID-19: A structured summary of a study protocol for a randomised controlled trial.COVID-19 住院成人患者使用伊马替尼的安全性和疗效:一项随机对照试验研究方案的结构化总结。
Trials. 2020 Oct 28;21(1):897. doi: 10.1186/s13063-020-04819-9.
5
Regarding Oculomotor Palsy After the Administration of the Messenger RNA-1273 Vaccine for SARS-CoV-2: Diplopia After the COVID-19 Vaccine.关于接种严重急性呼吸综合征冠状病毒2信使核糖核酸-1273疫苗后的动眼神经麻痹:新型冠状病毒肺炎疫苗接种后的复视
J Neuroophthalmol. 2023 Dec 1;43(4):e360. doi: 10.1097/WNO.0000000000001558. Epub 2022 Mar 24.
6
Transient Oculomotor Palsy Following the Administration of the Messenger RNA-1273 Vaccine for SARS-CoV-2 Diplopia Following the COVID-19 Vaccine.接种严重急性呼吸综合征冠状病毒2信使核糖核酸1273疫苗后出现短暂性动眼神经麻痹 接种新型冠状病毒肺炎疫苗后出现复视
J Neuroophthalmol. 2023 Mar 1;43(1):e14-e15. doi: 10.1097/WNO.0000000000001369. Epub 2021 Aug 4.
7
Clinical features and outcomes of Myasthenia Gravis associated with COVID-19 vaccines: A systematic review and pooled analysis.与 COVID-19 疫苗相关的重症肌无力的临床特征和结局:系统评价和汇总分析。
Medicine (Baltimore). 2023 Oct 6;102(40):e34890. doi: 10.1097/MD.0000000000034890.
8
Anosmia or Ageusia Following COVID-19 Vaccination: A Systematic Review.新冠疫苗接种后嗅觉丧失或味觉丧失:一项系统评价。
Ear Nose Throat J. 2024 Jun;103(1_suppl):164S-170S. doi: 10.1177/01455613241233098. Epub 2024 Feb 27.
9
Third Cranial Nerve Palsy Presenting with Unilateral Diplopia and Strabismus in a 24-Year-Old Woman with COVID-19.一名24岁感染新冠病毒的女性出现单侧复视和斜视,伴第三颅神经麻痹
Am J Case Rep. 2020 Oct 15;21:e925897. doi: 10.12659/AJCR.925897.
10
Reported cases of multisystem inflammatory syndrome in children aged 12-20 years in the USA who received a COVID-19 vaccine, December, 2020, through August, 2021: a surveillance investigation.2020年12月至2021年8月美国12至20岁接种新冠病毒疫苗儿童的多系统炎症综合征报告病例:一项监测调查。
Lancet Child Adolesc Health. 2022 May;6(5):303-312. doi: 10.1016/S2352-4642(22)00028-1. Epub 2022 Feb 23.

本文引用的文献

1
Ocular neuroinflammatory response secondary to SARS-CoV-2 infection-a review.严重急性呼吸综合征冠状病毒2(SARS-CoV-2)感染继发的眼部神经炎症反应——综述
Front Immunol. 2025 Feb 4;16:1515768. doi: 10.3389/fimmu.2025.1515768. eCollection 2025.
2
SARS-CoV-2 infects cells lining the blood-retinal barrier and induces a hyperinflammatory immune response in the retina via systemic exposure.严重急性呼吸综合征冠状病毒2(SARS-CoV-2)感染血视网膜屏障的内皮细胞,并通过全身暴露在视网膜中诱导超炎症免疫反应。
PLoS Pathog. 2024 Apr 10;20(4):e1012156. doi: 10.1371/journal.ppat.1012156. eCollection 2024 Apr.
3
Diplopia in Movement Disorders: A Systematic Review of the Literature.
运动障碍中的复视:文献系统综述
J Pers Med. 2024 Feb 29;14(3):270. doi: 10.3390/jpm14030270.
4
Clinical spectrum of ocular manifestations in COVID-19: a case series.COVID-19眼部表现的临床谱:病例系列
Infect Med (Beijing). 2023 Jun;2(2):148-152. doi: 10.1016/j.imj.2023.04.001. Epub 2023 Apr 13.
5
Ocular and Neuro-ophthalmic Manifestations Post COVID-19 Infection.新冠病毒感染后的眼部和神经眼科表现。
J Nepal Health Res Counc. 2023 Sep 10;21(1):184-186. doi: 10.33314/jnhrc.v21i1.4190.
6
The Clinical Course of New-Onset Ocular Myasthenia Gravis Caused by Pfizer-BioNTech COVID-19 Vaccine.辉瑞-生物科技新冠疫苗引起的新发眼肌型重症肌无力的临床病程。
Acta Neurol Taiwan. 2023 Dec 30;32(4):218-222.
7
Treatment of acquired partial oculomotor nerve palsy with dexamethasone - A case report.地塞米松治疗获得性部分动眼神经麻痹——病例报告
Int J Surg Case Rep. 2023 Sep;110:108757. doi: 10.1016/j.ijscr.2023.108757. Epub 2023 Sep 1.
8
COVID-19 and Crossed Eye: A Case Report and Literature Review.新型冠状病毒肺炎与斜视:一例报告及文献综述
Cureus. 2023 Jul 31;15(7):e42722. doi: 10.7759/cureus.42722. eCollection 2023 Jul.
9
Third cranial nerve palsy due to COVID-19 infection.因 COVID-19 感染导致的第三对颅神经麻痹。
BMJ Case Rep. 2023 May 3;16(5):e255142. doi: 10.1136/bcr-2023-255142.
10
Neuro-ophthalmic Manifestations of Coronavirus Disease 2019 and Its Vaccination: A Narrative Review.2019冠状病毒病及其疫苗接种的神经眼科表现:一项叙述性综述
J Ophthalmic Vis Res. 2023 Feb 21;18(1):113-122. doi: 10.18502/jovr.v18i1.12731. eCollection 2023 Jan-Mar.