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无神经损伤的胸腰段交界处创伤性A3爆裂骨折的经皮治疗:碎骨块阻滞的时机和特征对韧带整复效率的作用

Percutaneous Treatment of Traumatic A3 Burst Fractures of the Thoracolumbar Junction Without Neurological Impairment: The Role of Timing and Characteristics of Fragment Blocks on Ligamentotaxis Efficiency.

作者信息

De Robertis Mario, Anselmi Leonardo, Baram Ali, Tropeano Maria Pia, Morenghi Emanuela, Ajello Daniele, Cracchiolo Giorgio, Capo Gabriele, Tomei Massimo, Ortolina Alessandro, Fornari Maurizio, Brembilla Carlo

机构信息

Department of Biomedical Sciences, Humanitas University, Via Rita Levi Montalcini 4, 20072 Pieve Emanuele, Italy.

Department of Neurosurgery, IRCCS Humanitas Research Hospital, Via Manzoni 56, 20089 Rozzano, Italy.

出版信息

J Clin Med. 2025 Apr 17;14(8):2772. doi: 10.3390/jcm14082772.

DOI:10.3390/jcm14082772
PMID:40283602
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12027751/
Abstract

This study aims to evaluate how surgical timing and the radiological characteristics of fragment blocks can affect the effectiveness of ligamentotaxis, in restoring the spinal canal area, and local kyphosis in adults with traumatic thoracolumbar A3 burst fractures without neurological impairment treated with percutaneous short-segment fixation. A retrospective observational study was conducted between January 2016 and December 2022 on neurologically intact adult patients with a single A3 thoracolumbar fracture. Data collected included demographics, injury mechanism, fracture level, and clinical and surgical details. Radiological assessments included spinal canal area, local kyphotic angle, anterior and posterior vertebral heights, and fragment block measurements. Out of 101 treated patients, 9 met the criteria with a mean age of 52.22 years. Most fractures were at L1 (88.89%). All patients had moderate-to-severe pain (NRS 6.22 ± 1.09) at baseline. Five patients (55.55%) underwent surgery within 72 h, with a mean surgical time of 109.22 min. SCA and LKA values improved significantly in all patients post-surgery. Early surgical intervention (<72 h) correlated with greater improvements in spinal canal area ( = 0.016) and local kyphotic angle ( = 0.004). A significant association was found between spinal canal area improvement and the percentage ratio of fragment height to "normal" vertebral height (rho = 0.682; = 0.043). Early (<72 h) short-segment percutaneous fixation is recommended for adults with high functional demands and moderate-to-severe axial pain due to single traumatic A3N0M0 thoracolumbar fracture. This "upfront" approach is associated with enhanced indirect decompression and better local kyphotic angle restoration. Considering the fragment morphology could also be important in surgical planning.

摘要

本研究旨在评估手术时机和骨折块的放射学特征如何影响在经皮短节段固定治疗的无神经损伤的创伤性胸腰椎A3爆裂骨折成人患者中,韧带整复在恢复椎管面积和局部后凸方面的有效性。在2016年1月至2022年12月期间,对神经功能完整的单节段胸腰椎A3骨折成年患者进行了一项回顾性观察研究。收集的数据包括人口统计学、损伤机制、骨折节段以及临床和手术细节。放射学评估包括椎管面积、局部后凸角、椎体前后高度以及骨折块测量。在101例接受治疗的患者中,9例符合标准,平均年龄为52.22岁。大多数骨折发生在L1(88.89%)。所有患者在基线时均有中重度疼痛(NRS 6.22±1.09)。5例患者(55.55%)在72小时内接受了手术,平均手术时间为109.22分钟。所有患者术后椎管面积(SCA)和局部后凸角(LKA)值均显著改善。早期手术干预(<72小时)与椎管面积(p = 0.016)和局部后凸角(p = 0.004)的更大改善相关。发现椎管面积改善与骨折块高度与“正常”椎体高度的百分比比值之间存在显著关联(rho = 0.682;p = 0.043)。对于因单一创伤性A3N0M0胸腰椎骨折而有高功能需求和中重度轴向疼痛的成年人,建议早期(<72小时)短节段经皮固定。这种“早期”方法与增强的间接减压和更好的局部后凸角恢复相关。在手术规划中考虑骨折块形态也可能很重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2753/12027751/0063cfabc4b7/jcm-14-02772-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2753/12027751/9d5882d88f6f/jcm-14-02772-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2753/12027751/56aad8443c83/jcm-14-02772-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2753/12027751/2e0d1aed9cfd/jcm-14-02772-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2753/12027751/0063cfabc4b7/jcm-14-02772-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2753/12027751/9d5882d88f6f/jcm-14-02772-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2753/12027751/56aad8443c83/jcm-14-02772-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2753/12027751/2e0d1aed9cfd/jcm-14-02772-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2753/12027751/0063cfabc4b7/jcm-14-02772-g004.jpg

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本文引用的文献

1
Thoracolumbar Burst Fracture without Neurological Deficit: Review of Controversies and Current Evidence of Treatment.胸腰椎爆裂骨折无神经功能缺损:治疗争议与当前证据的综述。
World Neurosurg. 2022 Jun;162:29-35. doi: 10.1016/j.wneu.2022.03.061. Epub 2022 Mar 19.
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Indications for Nonsurgical Treatment of Thoracolumbar Spine Fractures: WFNS Spine Committee Recommendations.胸腰椎骨折非手术治疗的适应症:世界神经外科联合会脊柱委员会建议
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Incidence and Epidemiology of Thoracolumbar Spine Fractures: WFNS Spine Committee Recommendations.
胸腰椎骨折的发病率与流行病学:世界神经外科联合会脊柱委员会建议
Neurospine. 2021 Dec;18(4):704-712. doi: 10.14245/ns.2142418.209. Epub 2021 Dec 31.
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Surgical Techniques for Thoracolumbar Spine Fractures: WFNS Spine Committee Recommendations.胸腰椎骨折的手术技术:世界神经外科联合会脊柱委员会建议
Neurospine. 2021 Dec;18(4):667-680. doi: 10.14245/ns.2142206.253. Epub 2021 Dec 31.
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Rate and Predictors of Failure in the Conservative Management of Stable Thoracolumbar Burst Fractures: A Systematic Review and Meta-Analysis.稳定型胸腰椎爆裂骨折保守治疗失败的发生率及预测因素:一项系统评价与Meta分析
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Load-Sharing Classification Score as Supplemental Grading System in the Decision-Making Process for Patients With Thoracolumbar Injury Classification and Severity 4.用于胸腰椎损伤分类和严重程度 4 患者决策过程的分担分类评分作为补充分级系统。
Neurosurgery. 2021 Aug 16;89(3):428-434. doi: 10.1093/neuros/nyab179.
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Current state of benefits of Enhanced Recovery After Surgery (ERAS) in spinal surgeries: A systematic review of the literature.当前加速康复外科(ERAS)在脊柱手术中的获益状况:文献系统评价。
Neurochirurgie. 2022 Jan;68(1):61-68. doi: 10.1016/j.neuchi.2021.04.007. Epub 2021 Apr 24.
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Early Management of Spinal Cord Injury: WFNS Spine Committee Recommendations.脊髓损伤的早期管理:世界神经外科联合会脊柱委员会建议
Neurospine. 2020 Dec;17(4):759-784. doi: 10.14245/ns.2040366.183. Epub 2020 Dec 31.
9
Early fixation of traumatic spinal fractures and the reduction of complications in the absence of neurological injury: a retrospective cohort study from the American College of Surgeons Trauma Quality Improvement Program.创伤性脊柱骨折的早期固定与无神经损伤情况下并发症的减少:一项来自美国外科医师学会创伤质量改进项目的回顾性队列研究
J Neurosurg Spine. 2020 Aug 28;34(1):117-126. doi: 10.3171/2020.5.SPINE191440. Print 2021 Jan 1.
10
Necessity of Direct Decompression for Thoracolumbar Junction Burst Fractures with Neurological Compromise.伴有神经损伤的胸腰段爆裂骨折行直接减压的必要性
World Neurosurg. 2020 Oct;142:e413-e419. doi: 10.1016/j.wneu.2020.07.069. Epub 2020 Jul 18.