Fu Bing, Hu Lei, Ji Hui, Hou Ya-Feng
Department of Hepatobiliary Surgery, Tongling People's Hospital (Tongling Hospital Affiliated to Bengbu Medical University), Tongling 244000, Anhui Province, China.
World J Clin Oncol. 2025 Apr 24;16(4):100309. doi: 10.5306/wjco.v16.i4.100309.
With the aging global population, the decline in muscle mass and function among the elderly has emerged as a significant concern. This systemic progressive generalized loss of muscle function and mass is referred to as sarcopenia (SP). In recent years, a growing number of studies have investigated SP, revealing that many tumor diseases, especially in the digestive system, promote its occurrence due to the influence of the disease itself, diet, and other factors. Moreover, SP patients tend to have poorer postoperative recovery. At present, many diagnostic methods have been developed for SP, but no unified standard has been established. Furthermore, the cutoff values of many diagnostic methods for different populations are still in the exploratory stage, and additional clinical studies are required to explore these issues. This article comprehensively and systematically summarizes the diagnostic methods and criteria mentioned in previous research, focusing on the impact of SP on post-surgical patients with various malignant tumors.
随着全球人口老龄化，老年人肌肉质量和功能的下降已成为一个重大问题。这种全身性、进行性、普遍性的肌肉功能和质量丧失被称为肌肉减少症（SP）。近年来，越来越多的研究对SP进行了调查，发现许多肿瘤疾病，尤其是消化系统的肿瘤疾病，由于疾病本身、饮食和其他因素的影响，会促使其发生。此外，SP患者术后恢复往往较差。目前，已经开发出许多针对SP的诊断方法，但尚未建立统一的标准。此外，许多诊断方法针对不同人群的截断值仍处于探索阶段，需要更多的临床研究来探讨这些问题。本文全面系统地总结了以往研究中提到的诊断方法和标准，重点关注SP对各种恶性肿瘤术后患者的影响。
