Tang Xinyi, Huang Li, Yue Jirong, Qiu Li
Department of Medical Ultrasound and National Clinical Research Center for Geriatrics, West China Hospital of Sichuan University, Chengdu 610041, China.
National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu 610041, China.
J Biomech. 2025 Jun;186:112712. doi: 10.1016/j.jbiomech.2025.112712. Epub 2025 Apr 27.
Shear wave elastography (SWE) can quantify muscle stiffness to reflect the muscle quality, and we explored the application of SWE in assessing physical performance. In this work, a total of 98 older adults, including 55 men and 43 women, were recruited in this cross-sectional study. Short physical performance battery (SPPB) and time-up-and-go (TUG) test were used to evaluate physical performance, and a dynamic SWE imaging for the flexor digitorum superficialis in the process of using grip strength meter was documented. The peak strength and peak shear wave velocities (SWV) were recorded, and the ratio of peak SWV to peak strength was defined as the standardized muscle contractive stiffness. For men, the peak SWV was negatively correlated to SPPB scores (r = -0.351 to -0.448, all P < 0.01) and positively correlated to TUG time (r = 0.299-0.369, all P < 0.05), and the standardized muscle contractive stiffness was significantly negatively correlated to SPPB scores (r = -0.501 to -0.532, all P < 0.01) and positively correlated to TUG time (r = 0.424-0.462, all P < 0.01). For women, the peak SWV was not correlated to physical performance, and the standardized muscle contractive stiffness was correlated to the TUG time (r = 0.312 for Cmax and 0.310 for Cmean, both P < 0.05). Those participants with decreased physical performance had significant higher standardized muscle contractive stiffness in both men and women (all P < 0.05). We proved that SWE can be applied in evaluating muscle function and the flexor digitorum superficialis contractive stiffness standardized by grip strength can be a potential indicator.
剪切波弹性成像（SWE）可量化肌肉僵硬度以反映肌肉质量，我们探讨了SWE在评估身体机能方面的应用。在这项研究中，共有98名老年人参与了这项横断面研究，其中包括55名男性和43名女性。采用简易体能状况量表（SPPB）和计时起立行走测试（TUG）来评估身体机能，并记录了在使用握力计过程中示指浅屈肌的动态SWE成像。记录峰值力量和峰值剪切波速度（SWV），并将峰值SWV与峰值力量的比值定义为标准化肌肉收缩僵硬度。对于男性，峰值SWV与SPPB评分呈负相关（r = -0.351至-0.448，均P < 0.01），与TUG时间呈正相关（r = 0.299至0.369，均P < 0.05），标准化肌肉收缩僵硬度与SPPB评分呈显著负相关（r = -0.501至-0.532，均P < 0.01），与TUG时间呈正相关（r = 0.424至0.462，均P < 0.01）。对于女性，峰值SWV与身体机能无关，标准化肌肉收缩僵硬度与TUG时间相关（Cmax时r = 0.312，Cmean时r = 0.310，均P < 0.05）。身体机能下降的男性和女性参与者的标准化肌肉收缩僵硬度均显著更高（均P < 0.05）。我们证明SWE可用于评估肌肉功能，通过握力标准化的示指浅屈肌收缩僵硬度可能是一个潜在指标。
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