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女性复发性单纯性下尿路感染

Recurrent uncomplicated lower urinary tract infections in women.

作者信息

Liu Jiaxin, Xu Kaiyun, Hu Jiajie, Wang Lei, Liu Zhiyong

机构信息

Department of Urology, Changhai Hospital, Naval Medical University, Shanghai, China.

Department of Emergence, Eastern Hepatobiliary Surgery Hospital, Naval Medical University, Shanghai, China.

出版信息

Curr Urol. 2025 Mar;19(2):90-94. doi: 10.1097/CU9.0000000000000273. Epub 2025 Jan 23.

DOI:10.1097/CU9.0000000000000273
PMID:40314008
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12042170/
Abstract

Recurrent uncomplicated lower urinary tract infections (RULUTIs) are common among women without anatomical or physiological abnormalities and affect women of all age groups, races, and ethnicities. Herein, we summarized the sources of epidemiology, etiology, diagnosis, treatment, prophylaxis, and follow-up evaluations in cases of RULUTIs. Patients' medical histories, symptoms, and signs were recorded. The review showed that urinalysis, culture, and sensitivity should be tested before empiric treatment. A first-line therapeutic strategy should be applied based on the results of the urine culture and sensitivity tests. Therefore, estrogen should be used as an ancillary therapy. After the successful treatment of acute infections, intermittent or continuous prophylaxis can be administered. Patients may benefit from follow-up evaluations to avoid recurrent infections. We expect that clinicians will pay more attention to RULUTIs.

摘要

复发性单纯性下尿路感染(RULUTIs)在无解剖或生理异常的女性中很常见,影响所有年龄组、种族和民族的女性。在此,我们总结了RULUTIs病例的流行病学来源、病因、诊断、治疗、预防和随访评估。记录患者的病史、症状和体征。综述表明,在经验性治疗前应进行尿液分析、培养和药敏试验。应根据尿培养和药敏试验结果应用一线治疗策略。因此,雌激素应用作辅助治疗。急性感染成功治疗后,可进行间歇性或持续性预防。患者可能从随访评估中受益,以避免反复感染。我们期望临床医生将更多关注RULUTIs。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6caa/12042170/d244e79c6d6a/curr-urol-19-090-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6caa/12042170/d244e79c6d6a/curr-urol-19-090-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6caa/12042170/d244e79c6d6a/curr-urol-19-090-g001.jpg

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本文引用的文献

1
Efficacy of vaginal estrogen for recurrent urinary tract infection prevention in hypoestrogenic women.雌激素阴道制剂预防低雌激素女性复发性尿路感染的疗效。
Am J Obstet Gynecol. 2023 Aug;229(2):143.e1-143.e9. doi: 10.1016/j.ajog.2023.05.002. Epub 2023 May 11.
2
Cranberries for preventing urinary tract infections.蔓越莓预防尿路感染。
Cochrane Database Syst Rev. 2023 Apr 17;4(4):CD001321. doi: 10.1002/14651858.CD001321.pub6.
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Antibiotic prophylaxis for urinary tract infection.泌尿道感染的抗生素预防
Can Fam Physician. 2022 Dec;68(12):896. doi: 10.46747/cfp.6812896.
4
Significance of C-reactive Protein Levels in Categorizing Upper and Lower Urinary Tract Infection in Adult Patients.C反应蛋白水平在成年患者上、下尿路感染分类中的意义
Cureus. 2022 Jun 29;14(6):e26432. doi: 10.7759/cureus.26432. eCollection 2022 Jun.
5
Does Urinary pH and Diet Influence the Rate of Urinary Tract Infection Recurrence After Electrofulguration in Women With Antibiotic-Recalcitrant Recurrent Urinary Tract Infections?在抗生素难治性复发性尿路感染女性中,尿液 pH 值和饮食是否影响电灼术后尿路感染复发率?
Urology. 2022 Jun;164:94-99. doi: 10.1016/j.urology.2022.01.021. Epub 2022 Jan 23.
6
How to avoid drug resistance during treatment and prevention of urinary tract infections.如何在治疗和预防尿路感染期间避免耐药性。
Prz Menopauzalny. 2021 Dec;20(4):217-221. doi: 10.5114/pm.2021.111715. Epub 2021 Dec 9.
7
Recurrent Urinary Tract Infections and Asymptomatic Bacteriuria in Adults.成人复发性尿路感染和无症状菌尿症
Curr Bladder Dysfunct Rep. 2022;17(1):1-12. doi: 10.1007/s11884-021-00638-z. Epub 2021 Dec 1.
8
Management of uncomplicated recurrent urinary tract infections.单纯性复发性尿路感染的管理。
BJU Int. 2022 Jun;129(6):668-678. doi: 10.1111/bju.15630. Epub 2021 Nov 17.
9
Association of Adverse Events With Antibiotic Treatment for Urinary Tract Infection.抗生素治疗尿路感染不良事件的关联。
Clin Infect Dis. 2022 Apr 28;74(8):1408-1418. doi: 10.1093/cid/ciab637.
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Study of Bacterial Pathogens in Urinary Tract Infection and their Antimicrobial Sensitivity Pattern in the Setting of Gynecology Outpatient Department.妇科门诊尿路感染细菌病原体及其抗菌药敏模式的研究
Mymensingh Med J. 2020 Oct;29(4):838-846.