Soluble IgG aggregates produced by heating remain stable on freeze-drying.
作者信息
McCarthy D A, Field M, Mumford P, Moore S R, Holborow E J, Maini R N
出版信息
J Immunol Methods. 1985 Sep 3;82(1):155-60. doi: 10.1016/0022-1759(85)90234-0.
PMID:4031503
Abstract
IgG aggregates produced by heating gamma globulin solutions were freeze-dried, kept at 4 degrees C and reconstituted up to 4 months later. By comparison with frozen (-20 degrees C) preparations, only minimal changes in biological reactivity and in physical integrity occurred during this period. These results demonstrate that freeze-dried preparations of heat-aggregated IgG are potentially useful as a reference reagent for the comparative evaluation and standardisation of immune complex assays.
摘要
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