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年轻女性隐匿性原发性纵隔大B细胞淋巴瘤:一例报告及文献复习

Insidious Primary Mediastinal Large B-Cell Lymphoma in a Young Female: A Case Report and Literature Review.

作者信息

Gambhir Neil, Youn Paul, Mokhtari Moein Bayat, Kwan Patricia Lin, Aye Thida, Lam Wan Ling

机构信息

Department of Medicine, Lenox Hill Hospital, New York, New York, USA.

出版信息

Case Rep Oncol Med. 2025 Apr 26;2025:9983831. doi: 10.1155/crom/9983831. eCollection 2025.

Abstract

Primary mediastinal large B-cell lymphoma (PMBCL) is a highly aggressive malignancy primarily observed in female patients during their third decade of life. This rare condition, with an incidence of 0.4 per million, traditionally presents with B symptoms or compressive-based sequela such as SVC syndrome or respiratory distress. In this report, we present the case of a young female who presented for palpitations and tachycardia without cardiopulmonary compressive-based symptoms diagnosed with a large 16-cm infiltrative PMBCL localized in the left ventricle.

摘要

原发性纵隔大B细胞淋巴瘤(PMBCL)是一种侵袭性很强的恶性肿瘤,主要见于30岁左右的女性患者。这种罕见疾病的发病率为百万分之0.4,传统上表现为B症状或基于压迫的后遗症,如腔静脉综合征或呼吸窘迫。在本报告中,我们介绍了一名年轻女性的病例,她因心悸和心动过速就诊,无基于心肺压迫的症状,被诊断为位于左心室的一个16厘米大的浸润性PMBCL。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/192b/12049244/4d8bedacf708/CRIONM2025-9983831.001.jpg

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