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J-Valve系统经导管主动脉瓣置换术的八年临床结果

Eight-Year Clinical Outcomes of Transcatheter Aortic Valve Replacement with J-Valve System.

作者信息

Li Fei, Wang Yuetang, Xu Donghui, Wang Xu, Wang Wei

机构信息

Heart Valve and Atrial Fibrillation Center, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.

Department of Structural Heart Disease, Fuwai Hospital, Chinese Academy of Medical Sciences, Beijing, China.

出版信息

Ann Thorac Cardiovasc Surg. 2025;31(1). doi: 10.5761/atcs.oa.24-00152.


DOI:10.5761/atcs.oa.24-00152
PMID:40335318
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12055277/
Abstract

PURPOSE: This study aimed to summarize 8-year clinical outcomes for patients who underwent transcatheter aortic valve replacement (TAVR) with the J-Valve system and evaluate the long-term durability and hemodynamic performance of the valve. METHODS: Between July 2014 and June 2015, 21 patients underwent transapical TAVR with the J-Valve system. Systematic clinical and echocardiographic follow-up was conducted on 18 patients for up to 8 years. RESULTS: Eight years post-TAVR with the J-Valve system, the all-cause mortality rate was 16.7%, with no prosthesis failures or thrombosis. Moderate to severe valve deterioration was observed in 50% of patients with aortic stenosis (AS), whereas no such deterioration was noted in patients with pure aortic regurgitation (PAR). At 8 years following TAVR, the effective orifice area measured 2.27 ± 0.50 cm in patients with PAR and 1.35 ± 0.38 cm in those with AS. Additionally, patients with AS exhibited a mean pressure gradient of 17.90 ± 10.61 mmHg. Over 8 years, PAR patients experienced a significant reduction in left ventricular end-diastolic diameter from 61.50 ± 2.08 mm to 48.67 ± 7.23 mm (p < 0.001), whereas AS patients showed no significant change. CONCLUSION: The J-Valve system demonstrates favorable long-term outcomes in TAVR, with excellent durability and hemodynamic performance in PAR patients.

摘要

目的:本研究旨在总结接受J-Valve系统经导管主动脉瓣置换术(TAVR)患者的8年临床结局,并评估该瓣膜的长期耐用性和血流动力学性能。 方法:2014年7月至2015年6月期间,21例患者接受了使用J-Valve系统的经心尖TAVR。对18例患者进行了长达8年的系统临床和超声心动图随访。 结果:使用J-Valve系统进行TAVR术后8年,全因死亡率为16.7%,未发生人工瓣膜故障或血栓形成。在50%的主动脉瓣狭窄(AS)患者中观察到中度至重度瓣膜退化,而在单纯主动脉瓣反流(PAR)患者中未观察到此类退化。TAVR术后8年,PAR患者的有效瓣口面积为2.27±0.50平方厘米,AS患者为1.35±0.38平方厘米。此外,AS患者的平均压力阶差为17.90±10.61毫米汞柱。在8年期间,PAR患者的左心室舒张末期直径从61.50±2.08毫米显著减小至48.67±7.23毫米(p<0.001),而AS患者无显著变化。 结论:J-Valve系统在TAVR中显示出良好的长期结局,在PAR患者中具有出色的耐用性和血流动力学性能。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b728/12055277/07b3a281c2ad/atcs-31-1-24-00152-figure04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b728/12055277/34a3b0b78cc0/atcs-31-1-24-00152-figure01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b728/12055277/9a6a7c7862e8/atcs-31-1-24-00152-figure02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b728/12055277/49f52b933395/atcs-31-1-24-00152-figure03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b728/12055277/07b3a281c2ad/atcs-31-1-24-00152-figure04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b728/12055277/34a3b0b78cc0/atcs-31-1-24-00152-figure01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b728/12055277/9a6a7c7862e8/atcs-31-1-24-00152-figure02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b728/12055277/49f52b933395/atcs-31-1-24-00152-figure03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b728/12055277/07b3a281c2ad/atcs-31-1-24-00152-figure04.jpg

相似文献

[1]
Eight-Year Clinical Outcomes of Transcatheter Aortic Valve Replacement with J-Valve System.

Ann Thorac Cardiovasc Surg. 2025

[2]
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Circ Cardiovasc Interv. 2018-9

[3]
Self-Expanding Transcatheter Aortic Valve Replacement Versus Surgical Valve Replacement in Patients at High Risk for Surgery: A Study of Echocardiographic Change and Risk Prediction.

Circ Cardiovasc Interv. 2016-6

[4]
Echocardiographic Results of Transcatheter Versus Surgical Aortic Valve Replacement in Low-Risk Patients: The PARTNER 3 Trial.

Circulation. 2020-5-12

[5]
Transapical transcatheter aortic valve replacement with a novel transcatheter aortic valve replacement system in high-risk patients with severe aortic valve diseases.

J Thorac Cardiovasc Surg. 2017-9-15

[6]
Structural Valve Deterioration after Transcatheter Aortic Valve Implantation Using J-Valve: A Long-Term Follow-Up.

Ann Thorac Cardiovasc Surg. 2020-6-20

[7]
1-Year Results in Patients Undergoing Transcatheter Aortic Valve Replacement With Failed Surgical Bioprostheses.

JACC Cardiovasc Interv. 2017-5-22

[8]
Outcomes of Transcatheter Aortic Valve Replacement in Mixed Aortic Valve Disease.

JACC Cardiovasc Interv. 2019-10-30

[9]
5-Year Outcomes After TAVR With Balloon-Expandable Versus Self-Expanding Valves: Results From the CHOICE Randomized Clinical Trial.

JACC Cardiovasc Interv. 2020-4-15

[10]
Outcomes of Redo Transcatheter Aortic Valve Replacement for the Treatment of Postprocedural and Late Occurrence of Paravalvular Regurgitation and Transcatheter Valve Failure.

Circ Cardiovasc Interv. 2016-9

本文引用的文献

[1]
Transcatheter aortic valve implantation in patients with high-risk symptomatic native aortic regurgitation (ALIGN-AR): a prospective, multicentre, single-arm study.

Lancet. 2024-4-13

[2]
Transcatheter or surgical aortic valve implantation: 10-year outcomes of the NOTION trial.

Eur Heart J. 2024-4-1

[3]
Transcatheter Aortic-Valve Replacement in Low-Risk Patients at Five Years.

N Engl J Med. 2023-11-23

[4]
Progressing Forward in Transcatheter Aortic Valve Replacement for Pure Aortic Regurgitation.

JACC Cardiovasc Interv. 2023-8-28

[5]
Transcatheter Treatment of Native Aortic Valve Regurgitation: The North American Experience With a Novel Device.

JACC Cardiovasc Interv. 2023-8-28

[6]
Transcatheter aortic valve implantation using the SAPIEN 3 valve to treat aortic regurgitation: The French multicentre S3AR study.

Arch Cardiovasc Dis. 2023-2

[7]
Transcatheter Aortic Valve Replacement in Pure Native Aortic Valve Regurgitation: Challenging Pathology Awaiting Specialized Devices.

Aorta (Stamford). 2021-4

[8]
Eight-year outcomes for patients with aortic valve stenosis at low surgical risk randomized to transcatheter vs. surgical aortic valve replacement.

Eur Heart J. 2021-8-7

[9]
2020 ACC/AHA Guideline for the Management of Patients With Valvular Heart Disease: Executive Summary: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines.

Circulation. 2021-2-2

[10]
Transcatheter Aortic Valve Replacement vs Surgical Replacement in Patients With Pure Aortic Insufficiency.

Mayo Clin Proc. 2020-12

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