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高龄初产妇住院时急诊剖宫产的影响因素分析及预测模型

Influencing Factor Analysis and Prediction Model of Emergency Caesarean Delivery for Advanced-Age Nulliparous Women at the Time of Hospitalization.

作者信息

Arakaki Ryosuke, Isono Wataru, Fukuda Hiroaki, Tanaka Junya, Minamino Arisa, Hayashi Shiko

机构信息

Department of Obstetrics and Gynaecology, Kinan Hospital, Wakayama, Japan.

Department of Obstetrics and Gynecology, Wakayama Medical University, Kimiidera, Japan.

出版信息

J Family Reprod Health. 2024 Dec;18(4):217-225. doi: 10.18502/jfrh.v18i4.17410.

Abstract

OBJECTIVE

In Japan, the number of nulliparous pregnant women of advanced age, defined as 35 years or older, has increased, and the age range has lengthened towards older age with the increased use of infertility treatments. Given this trend, adverse labour outcomes, such as emergency caesarean delivery (ECD), are expected to increase. Therefore, by focusing mainly on maternal age and infertility treatment history, we aimed to establish a new prediction model for the likelihood of ECD after identifying the influencing factors related to maternal and labour-related characteristics.

MATERIALS AND METHODS

The medical records of 1,521 pregnant women who were nulliparous between 2017/4/1 and 2024/3/31 at our hospital were retrospectively reviewed. First, for the 675 women who were aged 30 years old or more, we calculated the rates of ECD in 8 groups classified according to maternal age, infertility treatment, and other variables. Next, we performed multivariate logistic regression analysis to assess the effect of each representative factor and established a prediction model based on the number of factors that were significant in the multivariate analysis.

RESULTS

Simple comparisons classified by maternal age revealed a constant increase in the rate of ECD with increasing maternal age, and multivariate analysis revealed 7 significant factors, namely, advanced maternal age, history of using assisted reproductive techniques (ART), small height, high Body mass index (BMI), low Bishop score, late-term delivery, and large infant. In the prediction model constructed with these 7 factors, the rate of ECD increased as the number of these factors increased.

CONCLUSION

The negative impact of advanced maternal age, namely, 40 years or older, and ART history, on labour outcome is clear. A new prediction model has the potential to identify patients with an extremely high probability of needing an ECD. These results may indicate that the management of the labour process will become more difficult in the future.

摘要

目的

在日本,35岁及以上的高龄未生育孕妇数量有所增加,随着不孕治疗的使用增加,年龄范围也向更高龄延长。鉴于这种趋势,预计诸如急诊剖宫产(ECD)等不良分娩结局将会增加。因此,我们主要关注产妇年龄和不孕治疗史,旨在在确定与产妇及分娩相关特征的影响因素后,建立一个预测急诊剖宫产可能性的新模型。

材料与方法

回顾性分析了我院2017年4月1日至2024年3月31日期间1521例未生育孕妇的病历。首先,对于675例30岁及以上的孕妇,我们计算了根据产妇年龄、不孕治疗及其他变量分类的8组中的急诊剖宫产率。接下来,我们进行多因素逻辑回归分析以评估每个代表性因素的影响,并基于多因素分析中有显著意义的因素数量建立了一个预测模型。

结果

按产妇年龄进行的简单比较显示,急诊剖宫产率随着产妇年龄的增加而持续上升,多因素分析显示有7个显著因素,即高龄产妇、使用辅助生殖技术(ART)史、身高矮小、高体重指数(BMI)、低Bishop评分、晚期分娩和巨大儿。在由这7个因素构建的预测模型中,急诊剖宫产率随着这些因素数量的增加而上升。

结论

高龄产妇(即40岁及以上)和ART史对分娩结局的负面影响是明显的。一个新的预测模型有可能识别出极有可能需要急诊剖宫产的患者。这些结果可能表明未来分娩过程的管理将变得更加困难。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a3df/12056442/064f4502bf21/JFRH-18-217-g001.jpg

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