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床旁超声(POCUS)检测肾移植后全身静脉充血的患病率。

The Prevalence of Systemic Venous Congestion Post Kidney Transplant Detected by Point of Care Ultrasound (POCUS).

作者信息

Beltramino Santiago, Bruno Agustín Manchado, Fernández Damián, Walther Javier, Werber Gustavo

机构信息

Intensive Care Unit, Instituto de Trasplante y Alta Complejidad. Buenos Aires, ARG.

Kidney Transplant Unit, Instituto de Trasplante y Alta Complejidad. Buenos Aires, ARG.

出版信息

POCUS J. 2025 Apr 15;10(1):134-140. doi: 10.24908/pocusj.v10i01.18260. eCollection 2025 Apr.

Abstract

Systemic venous congestion is a known cause of acute kidney injury (AKI), but its presence in kidney transplant patients has not been previously described in the literature. The objective of this study was to determine the prevalence of systemic venous congestion in recent kidney transplant recipients. We conducted a prospective, longitudinal, descriptive study including 30 adult patients during the first week post-renal transplant at the Instituto de Trasplante y Alta Complejidad in Buenos Aires, Argentina. Venous congestion was detected in 53% of patients (16/30), but only 13.3% (4/30) presented moderate to severe congestion. Pulmonary congestion was more frequent: 70% (21/30) of the patients presented some degree of pulmonary congestion, and 30% (9/30) had moderate or severe congestion. In the venous congestion group, 75% of patients developed delayed graft function (DGF) compared to 57% in the non-congestion group, although this difference was not statistically significant (p<0.3). Body weight and physical examination-two commonly used methods to guide decisions on dialysis initiation and fluid management-were found to be unreliable for assessing the true volume status. In conclusion, venous congestion was observed during the first week following renal transplantation; however, moderate to severe congestion was uncommon, affecting only 13.3% of patients. While DGF was more frequently observed in patients with congestion, a statistically significant association could not be established. Further studies with larger sample sizes are needed to better evaluate this potential relationship.

摘要

全身静脉淤血是急性肾损伤(AKI)的已知病因,但此前文献中尚未描述其在肾移植患者中的存在情况。本研究的目的是确定近期肾移植受者中全身静脉淤血的患病率。我们在阿根廷布宜诺斯艾利斯的移植与高复杂性研究所进行了一项前瞻性、纵向、描述性研究,纳入了30例成年肾移植术后第一周的患者。53%(16/30)的患者检测到静脉淤血,但只有13.3%(4/30)出现中度至重度淤血。肺淤血更为常见:70%(21/30)的患者出现一定程度的肺淤血,30%(9/30)有中度或重度淤血。在静脉淤血组中,75%的患者发生移植肾功能延迟恢复(DGF),而非淤血组为57%,尽管这一差异无统计学意义(p<0.3)。体重和体格检查——这两种常用于指导透析开始和液体管理决策的方法——被发现对于评估真实容量状态并不可靠。总之,肾移植术后第一周观察到静脉淤血;然而,中度至重度淤血并不常见,仅影响13.3%的患者。虽然淤血患者中更常观察到DGF,但未能建立统计学上的显著关联。需要更大样本量的进一步研究来更好地评估这种潜在关系。

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