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青少年毛囊性蕈样肉芽肿病例报告:一种易误诊的疾病。

A Case Report on Juvenile Folliculotropic Mycosis Fungoides: A Misleading Disease.

作者信息

Mansour Billah Lamia, Kelati Awatef

机构信息

Dermatology Unit, Cheikh Khalifa International University Hospital, Casablanca, MAR.

出版信息

Cureus. 2025 Apr 10;17(4):e82009. doi: 10.7759/cureus.82009. eCollection 2025 Apr.

Abstract

Mycosis fungoides (MF) is the most common form of cutaneous T-cell lymphoma, usually affecting elderly patients. Folliculotropic mycosis fungoides (FMF) is a subtype of MF that affects the hair follicles. While it is the most common variant in adults, it is rarely described in the pediatric population. The clinical manifestations of FMF can mimic common childhood dermatoses, like atopic dermatitis (AD), which often leads to a delay in diagnosis. In the pediatric population, FMF is usually diagnosed at an early stage, and its course is often indolent. There are no guidelines for pediatric FMF; treatment is generally based on the approach used in adults and responds well to phototherapy combining narrow band ultraviolet B (NbUVB) and UVA. We report the case of an 11-year-old child who was treated for several years for atopic dermatitis with follicular involvement, revealing an FMF. This case highlights the value of clinicians' persistence in diagnosing and managing such a rare condition, as well as the essential role of the dermoscopic tool in identifying patterns that may improve the early diagnosis of MF.

摘要

蕈样肉芽肿(MF)是皮肤T细胞淋巴瘤最常见的形式,通常影响老年患者。亲毛囊性蕈样肉芽肿(FMF)是MF的一种亚型,会影响毛囊。虽然它是成人中最常见的变体,但在儿科人群中很少被描述。FMF的临床表现可能类似于常见的儿童皮肤病,如特应性皮炎(AD),这常常导致诊断延迟。在儿科人群中,FMF通常在早期被诊断出来,其病程通常较为缓慢。目前尚无针对儿童FMF的指南;治疗通常基于成人使用的方法,对窄带紫外线B(NbUVB)和UVA联合光疗反应良好。我们报告了一例11岁儿童的病例,该儿童因伴有毛囊受累的特应性皮炎接受了数年治疗,最终被诊断为FMF。该病例突出了临床医生在诊断和管理这种罕见疾病时坚持不懈的价值,以及皮肤镜工具在识别可能改善MF早期诊断的模式方面的重要作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a8a6/12065962/da830593b6dc/cureus-0017-00000082009-i01.jpg

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