Chauhan Sanshriti, Gulati Sanjeev, Naorem Gopendro Singh
Department of Nephrology, Fortis Health Care Limited, New Delhi, India.
Department of Histopathology, Fortis Health Care Limited, New Delhi, India.
Indian J Nephrol. 2025 May-Jun;35(3):436-438. doi: 10.25259/IJN_2_2024. Epub 2024 Jul 8.
Cryptococcal infections are notoriously difficult to diagnose and have been associated with high morbidity and mortality. presenting as osteomyelitis is an unexpected clinical scenario in the transplant ward. A young male who underwent spousal kidney donor transplantation 16 months ago presented with painful and ulcerated soft tissue in upper and lower limbs which were diagnosed as cryptococcus osteomyelitis. He was managed with surgical debridement, liposomal amphotericin B, flucytosine and reduction in maintenance immunosuppression (IS). To our knowledge this is the first reported case of multifocal cryptococcus osteomyelitis in a kidney transplant recipient.
隐球菌感染 notoriously 难以诊断,且与高发病率和死亡率相关。在移植病房中,表现为骨髓炎是一种意想不到的临床情况。一名16个月前接受配偶肾移植的年轻男性出现上肢和下肢疼痛且溃疡的软组织,被诊断为隐球菌性骨髓炎。他接受了手术清创、脂质体两性霉素B、氟胞嘧啶治疗,并减少了维持性免疫抑制(IS)。据我们所知,这是首例报道的肾移植受者多灶性隐球菌性骨髓炎病例。