Budhwani Henna, Yigit Ibrahim, Nguyen Hoa L, Bruce Josh, Bond C Lily, Johnson Andrea
Institute on Digital Health and Innovation, College of Nursing, Florida State University, Tallahassee, FL, 32306, USA.
Department of Population and Quantitative Health Sciences, University of Massachusetts Chan Medical School, Worcester, MA, USA.
BMC Res Notes. 2025 May 12;18(1):210. doi: 10.1186/s13104-025-07273-5.
In the southern United States, adolescents are at elevated risk for HIV acquisition. In Alabama, school-based sexual health and HIV prevention education is strictly regulated and does not address the unique needs of sexual and gender minority (SGM) teenagers. To inform public health efforts, we assessed SGM adolescents' HIV prevention pre-exposure prophylaxis (PrEP) awareness and modality preferences by gender, race, and ethnicity.
Survey data were collected in 2023-2024 from SGM adolescents aged 14-17 years, lived in Alabama, with male sex assigned at birth (N = 206). Recruitment occurred online and in-person at a charter school. Data were analyzed using chi-squares and analysis of variance, controlling for age. Over half of respondents were sexually active, but only 26% had ever been tested for HIV. Half knew about PrEP. Of those with PrEP awareness, 41.9% were aware of daily pills; 32.3% of long-acting injectable PrEP. Pill-based PrEP was highly endorsed. Trans- and gender-non-conforming adolescents reported a greater preference for on-demand pill-based PrEP compared to men who have sex with men (p =.01). Non-Hispanics had a greater preference for a 6-month long-acting injectable option compared to Hispanic adolescents (p =.04). Findings suggest the need for HIV prevention interventions tailored to southern contexts and adolescent knowledge.
Not Applicable.
在美国南部，青少年感染艾滋病毒的风险较高。在阿拉巴马州，以学校为基础的性健康和艾滋病毒预防教育受到严格监管，并未满足性少数和性别少数（SGM）青少年的独特需求。为了为公共卫生工作提供信息，我们按性别、种族和族裔评估了SGM青少年对艾滋病毒预防暴露前预防（PrEP）的知晓情况和方式偏好。
2023年至2024年收集了居住在阿拉巴马州、出生时被指定为男性、年龄在14至17岁的SGM青少年的调查数据（N = 206）。通过在线和在一所特许学校进行面对面招募。使用卡方检验和方差分析对数据进行分析，并控制年龄因素。超过一半的受访者有性行为，但只有26%的人曾接受过艾滋病毒检测。一半的人知道PrEP。在了解PrEP的人中，41.9%的人知道每日服药；32.3%的人知道长效注射用PrEP。基于药丸的PrEP得到了高度认可。与男男性行为者相比，跨性别和性别不一致的青少年报告对按需服用药丸的PrEP有更大的偏好（p = 0.01）。与西班牙裔青少年相比，非西班牙裔对6个月长效注射选项有更大的偏好（p = 0.04）。研究结果表明需要针对南部地区情况和青少年知识水平量身定制艾滋病毒预防干预措施。
不适用。
