Åkerblom Sophia, McCracken Lance M, Rivano Fischer Marcelo, Perrin Sean
Department of Pain Rehabilitation, Skåne University Hospital, Lund, Sweden.
Department of Health Sciences, Lund University, Lund, Sweden.
Front Pain Res (Lausanne). 2025 Apr 28;6:1547540. doi: 10.3389/fpain.2025.1547540. eCollection 2025.
Little is known about whether the recommended, non-pharmacological treatments for chronic pain yield reductions in healthcare utilization, social costs and increased productivity in actual practice.
The primary aim of this study ( = 232) was to conduct secondary analyses of health economic outcomes using data from national registries combined with clinical outcome data from a large pain center in Sweden conducting multidisciplinary treatment based on a cognitive behavioral approach. Specifically, pain-related and health economic outcomes at post-treatment and one, two and three years after discharge were examined. In an exploratory fashion, we also investigated whether sociodemographic characteristics, pain-related variables, and psychological flexibility predicted these long-term pain-related and health economic outcomes. We also examined psychological flexibility as a potential mediator of these outcomes.
Small and moderate sized improvements in pain, pain interference, and depression observed at post-treatment were mostly maintained at both the 1- and 3-year follow-up. A very similar pattern was observed for health economic outcomes, with 1-year follow-up gains being maintained at long-term follow-up. Baseline psychological flexibility predicted long-term pain-related outcomes, but not health economic outcomes. Changes in psychological flexibility during treatment and follow-up mediated long-term pain-related outcomes and the total number of health care visits.
The present findings add to a small body of literature indicating that the improvements in pain and related difficulties following multidisciplinary, pain-focused, CBT programs persist at least three years following treatment, and these are accompanied by modest improvements in health economic outcomes over the same interval. Psychological flexibility seems to be predominately associated with long-term clinical outcomes in pain management, and it also appears relevant to the number of health care visits.
对于慢性疼痛推荐的非药物治疗在实际应用中是否能降低医疗保健利用率、社会成本并提高生产力,人们了解甚少。
本研究(n = 232)的主要目的是利用来自国家登记处的数据以及瑞典一个大型疼痛中心的临床结局数据进行健康经济结局的二次分析,该疼痛中心基于认知行为方法开展多学科治疗。具体而言,研究了治疗后以及出院后1年、2年和3年的疼痛相关和健康经济结局。以探索性方式,我们还调查了社会人口学特征、疼痛相关变量和心理灵活性是否能预测这些长期的疼痛相关和健康经济结局。我们还将心理灵活性作为这些结局的潜在中介因素进行了研究。
治疗后观察到的疼痛、疼痛干扰和抑郁方面的小到中度改善在1年和3年随访时大多得以维持。健康经济结局也观察到非常相似的模式,1年随访时的改善在长期随访中得以维持。基线心理灵活性预测了长期的疼痛相关结局,但未预测健康经济结局。治疗和随访期间心理灵活性的变化介导了长期的疼痛相关结局和医疗就诊总数。
本研究结果补充了一小部分文献,表明多学科、以疼痛为重点的认知行为疗法项目治疗后疼痛及相关问题的改善至少持续三年,并且在此期间健康经济结局也有适度改善。心理灵活性似乎主要与疼痛管理的长期临床结局相关,并且它似乎也与医疗就诊次数有关。