Han Mingyang, Sun Yuan, Li Minyi, Sui Xinru, Feng Junwen, Wang Dongyang
School of Environmental and Chemical Engineering, Jiangsu University of Science and Technology, Jiangsu Province, Zhenjiang, 212003, China.
College of Biological and Chemical Engineering, Qilu Institute of Technology, Jinan, 250200, China.
Mikrochim Acta. 2025 May 13;192(6):350. doi: 10.1007/s00604-025-07199-6.
Dihydroxybenzenes, including hydroquinone (HQ), catechol (CC) and resorcinol (RS), are important environmental pollutants that poses a serious threat to human health at high concentrations. Accurately and rapidly detecting dihydroxyphenyl groups in actual samples is of great significance for environmental monitoring and protection. Electrochemical sensors, as a fast and convenient analytical tool, have long had bottlenecks such as poor specificity. Here, an electrochemical sensor has been developed with nitrogen-doped Mo₂C/C nanocomposites as the sensing catalyst for simultaneous detection of HQ, CC and RS. The oxidation peak potentials of HQ, CC and RS on MoC/C/GCE were -0.05 V, 0.16 V and 0.50 V (vs. Ag/AgCl) respectively, indicating that the electrochemical oxidation processes of the three dihydroxyphenyl isomers were independent and do not interfere with each other. The responses to HQ, CC, and RS exhibit linear relationships within the ranges 0.5 ~ 1000 μM, 1.0 ~ 1000 μM and 2.0 ~ 900 μM, respectively. The corresponding detection limits are 0.13, 0.15 and 0.85 μM (S/N = 3), respectively. Moreover, MoC/C/GCE exhibits excellent anti-interference, repeatability, reproducibility, and stability in the simultaneous detection of HQ, CC, and RS, providing clear evidence for the application of MoC/C/GCE in analysis of actual water samples.
二羟基苯，包括对苯二酚（HQ）、邻苯二酚（CC）和间苯二酚（RS），是重要的环境污染物，高浓度时会对人类健康构成严重威胁。准确快速地检测实际样品中的二羟基苯基对于环境监测和保护具有重要意义。电化学传感器作为一种快速便捷的分析工具，长期以来存在特异性差等瓶颈问题。在此，已开发出一种以氮掺杂的Mo₂C/C纳米复合材料作为传感催化剂的电化学传感器，用于同时检测HQ、CC和RS。HQ、CC和RS在MoC/C/GCE上的氧化峰电位分别为-0.05 V、0.16 V和0.50 V（相对于Ag/AgCl），表明这三种二羟基苯基异构体的电化学氧化过程相互独立，互不干扰。对HQ、CC和RS的响应分别在0.5 ~ 1000 μM、1.0 ~ 1000 μM和2.0 ~ 900 μM范围内呈现线性关系。相应的检测限分别为0.13、0.15和0.85 μM（S/N = 3）。此外，MoC/C/GCE在同时检测HQ、CC和RS时表现出优异的抗干扰性、重复性、再现性和稳定性，为MoC/C/GCE在实际水样分析中的应用提供了明确依据。
