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脊柱或胸部畸形儿童胸部呼吸运动分辨磁共振成像技术:全面概述

Techniques for Respiratory Motion-Resolved Magnetic Resonance Imaging of the Chest in Children with Spinal or Chest Deformities: A Comprehensive Overview.

作者信息

Arias-Martínez Paula, Lafranca Peter P G, Mohamed Hoesein Firdaus A A, Vincken Koen, Schlösser Tom P C

机构信息

University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands.

出版信息

J Clin Med. 2025 Apr 23;14(9):2916. doi: 10.3390/jcm14092916.

Abstract

Quantification of the severity of chest wall deformation in children with spinal deformities is essential for understanding the effects on trunk appearance and cardiopulmonary function. Magnetic resonance imaging (MRI) is particularly valuable for this purpose, as it does not employ ionizing radiation and can provide three-dimensional (3D) imaging of thoracic anatomy. Acquiring sufficient quality images of the chest wall, lungs and airways at key stages of the respiratory cycle, such as end-inspiratory or expiratory phase, is crucial for accurately assessing chest wall deformation and pulmonary function and mechanics. Regarding image quality, low proton density and short relaxation times of the lung tissues result in poor quality images, and long acquisition times result in blurring caused by respiratory and cardiac motion. This overview summarizes strategies developed to address the inherent challenges of visualization of lung tissue and respiratory motion in MRI acquisition of the chest of pediatric patients with spinal deformities. An overview of the main methods for motion-resolved image acquisition and measurement of chest wall motion and thoracic volumes is presented and discussed. It is concluded that despite the development of multiple techniques and diverse strategies for obtaining high-quality, motion-resolved chest MRI, further validation of these methods is required before their implementation in clinics for routine evaluation of chest deformation in pediatric spinal deformity patients.

摘要

量化脊柱畸形患儿胸壁畸形的严重程度对于了解其对躯干外观和心肺功能的影响至关重要。磁共振成像(MRI)在此方面具有特别的价值,因为它不使用电离辐射,并且能够提供胸部解剖结构的三维(3D)成像。在呼吸周期的关键阶段,如吸气末或呼气末,获取足够质量的胸壁、肺部和气道图像对于准确评估胸壁畸形以及肺功能和力学情况至关重要。关于图像质量,肺组织的低质子密度和短弛豫时间会导致图像质量不佳,而长采集时间会因呼吸和心脏运动导致图像模糊。本综述总结了为应对小儿脊柱畸形患者胸部MRI采集过程中肺组织可视化和呼吸运动的固有挑战而开发的策略。本文介绍并讨论了运动分辨图像采集以及胸壁运动和胸廓容积测量的主要方法。得出的结论是,尽管已经开发出多种获取高质量、运动分辨胸部MRI的技术和不同策略,但在将这些方法应用于临床以常规评估小儿脊柱畸形患者的胸部畸形之前,还需要进一步验证。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f295/12072363/34ee451608d3/jcm-14-02916-g001.jpg

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