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使用八瓣技术行白内障超声乳化术后浅前房眼中的角膜内皮细胞丢失

Corneal Endothelial Cell Loss in Shallow Anterior Chamber Eyes After Phacoemulsification Using the Eight-Chop Technique.

作者信息

Sato Tsuyoshi

机构信息

Department of Ophthalmology, Sato Eye Clinic, Nemoto 3-3, Matsudo-shi 271-0077, Chiba-ken, Japan.

出版信息

J Clin Med. 2025 Apr 28;14(9):3045. doi: 10.3390/jcm14093045.

Abstract

In this study, the correlation between anterior chamber depth (ACD) and corneal endothelial cell density (CECD) loss was evaluated, and an assessment was made of the safety and efficacy of the eight-chop technique in cataract surgery for patients with shallow anterior chamber (SAC) depth. The technique was applied to patients with SAC and normal ACD, defined as <3 mm and ≥3 mm, respectively. Best-corrected visual acuity (BCVA), intraocular pressure (IOP), CECD, coefficient of variation, percentage of hexagonal cells, and central corneal thickness were assessed pre- and postoperatively. Operative time, phaco time, aspiration time, cumulative dissipated energy (CDE), and volume of fluid used were recorded intraoperatively. A total of 180 eyes from 99 patients (mean age, 74.8 ± 5.1 years; 28 men, 71 women) were analyzed. In the SAC group, the mean operative time, phaco time, aspiration time, CDE, and volume of fluid used were 4.7 min, 15.4 s, 65.6 s, 5.87, and 26.6 mL, respectively, demonstrating favorable surgical metrics. CECD loss was 1.3% at 7 weeks, 1.1% at 19 weeks, and 0.9% at 1 year, with no significant decrease after surgery in the SAC group. No correlation was observed between CECD loss and ACD in either group. These findings suggest that the eight-chop technique is a minimally invasive and effective approach that preserves corneal endothelial integrity, even in patients with SAC depth.

摘要

在本研究中,评估了前房深度(ACD)与角膜内皮细胞密度(CECD)损失之间的相关性,并对浅前房(SAC)深度患者白内障手术中八瓣技术的安全性和有效性进行了评估。该技术分别应用于SAC且前房深度正常(分别定义为<3 mm和≥3 mm)的患者。术前和术后评估最佳矫正视力(BCVA)、眼压(IOP)、CECD、变异系数、六角形细胞百分比和中央角膜厚度。术中记录手术时间、超声乳化时间、抽吸时间、累积耗散能量(CDE)和所用液体量。共分析了99例患者的180只眼(平均年龄74.8±5.1岁;男性28例,女性71例)。在SAC组中,平均手术时间、超声乳化时间、抽吸时间、CDE和所用液体量分别为4.7分钟、15.4秒、65.6秒、5.87和26.6毫升,显示出良好的手术指标。SAC组术后7周CECD损失为1.3%,19周为1.1%,1年为0.9%,术后无显著下降。两组中均未观察到CECD损失与ACD之间的相关性。这些发现表明,八瓣技术是一种微创且有效的方法,即使对于SAC深度的患者也能保持角膜内皮的完整性。

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