Oepen G, Schulz-Weiling R, Zimmermann P, Birg W, Straesser S, Gilsbach J
Acta Neurochir (Wien). 1985;77(1-2):22-8. doi: 10.1007/BF01402301.
Ten patients with partial callosal lesions were investigated with a broad scale neuropsychological assessment. Nine patients with a variety of lesions affecting midline structures have been operated using a direct transcallosal approach, one patient with a callosal lipoma remained unoperated. Sophisticated studies of the interhemispheric transfer of somaesthetic and perceptual motor tasks, as well as psychometric testing related to parameters of memory and attention performance were applied. The results indicate that there is no clear correlation between the site of callosal lesion and clinical symptoms. Although special disconnecting symptoms due to callosal dissection could be found, they didn't reach clinical significance. The most severe symptoms of impairment were caused by the extracallosal pathology. The results indicate that the transcallosal approach is a safe and feasible alternative in the management of pathological lesions in the midline region.
对10例胼胝体部分损伤患者进行了广泛的神经心理学评估。9例患有影响中线结构的各种损伤的患者采用经胼胝体直接入路进行了手术，1例患有胼胝体脂肪瘤的患者未接受手术。应用了对躯体感觉和感知运动任务半球间传递的精细研究，以及与记忆和注意力表现参数相关的心理测量测试。结果表明，胼胝体损伤部位与临床症状之间没有明显的相关性。虽然可以发现由于胼胝体切开导致的特殊分离症状，但它们未达到临床意义。最严重的损伤症状是由胼胝体外病变引起的。结果表明，经胼胝体入路是中线区域病理性病变管理中的一种安全可行的替代方法。
