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一名接受血液透析的系统性红斑狼疮患者因猫咬伤引发菌血症:病例报告

bacteremia associated with a cat bite in a patient with systemic lupus erythematosus on hemodialysis: A case report.

作者信息

Nakao Masahiko, Hosokawa Naoto, Ziren Wang, Yamamoto Takeru, Ebisu Yosuke, Watanabe Naoki, Watari Tomohisa, Otsuka Yoshihito, Osawa Ryosuke

机构信息

Department of Infectious Diseases, Kameda Medical Center, Chiba, Japan.

Department of Clinical Laboratory, Kameda Medical Center, Chiba, Japan.

出版信息

IDCases. 2025 Apr 29;40:e02240. doi: 10.1016/j.idcr.2025.e02240. eCollection 2025.

Abstract

The genus , which is part of the oral microbiome of both humans and animals, has the potential to cause severe infections in humans following animal bites. A 59-year-old man with systemic lupus erythematosus (SLE) on hemodialysis presented with cellulitis of the left upper limb after being bitten by his cat and was admitted to our hospital. Blood cultures were obtained, and empiric treatment with ampicillin/sulbactam was initiated. The patient developed a non-severe drug eruption on the 3rd hospital day, prompting a switch to ceftriaxone. Thin spindle-shaped Gram-negative bacilli were isolated from the blood cultures 127 h (5 days and 7 h) after obtained blood sample, and the patient completed a 2-weeks course of ceftriaxone with complete recovery. The isolate was identified as by MALDI-TOF MS and 16S rRNA gene sequencing. This case highlights the importance of considering in cat bite-associated infections. Obtaining blood cultures and extending incubation periods may be crucial for identifying the causative pathogen and guiding appropriate treatment in such cases.

摘要

该菌属是人类和动物口腔微生物群的一部分,动物咬伤后有可能在人类中引起严重感染。一名59岁接受血液透析的系统性红斑狼疮(SLE)男性患者,被猫咬伤后出现左上肢蜂窝织炎,入住我院。采集了血培养样本,并开始用氨苄西林/舒巴坦进行经验性治疗。患者在住院第3天出现轻度药物疹,促使改用头孢曲松。在采集血样127小时(5天7小时)后,从血培养物中分离出细梭形革兰氏阴性杆菌,患者完成了为期2周的头孢曲松治疗,完全康复。通过基质辅助激光解吸电离飞行时间质谱(MALDI-TOF MS)和16S rRNA基因测序将分离株鉴定为[具体菌名未给出]。该病例强调了在猫咬伤相关感染中考虑[具体菌名未给出]的重要性。采集血培养样本并延长培养时间对于识别致病病原体和在此类病例中指导适当治疗可能至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0320/12076798/edfdc93ec202/gr1.jpg

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