Hadi Fazal, Sardar Haseeba, Alam Waqas, Aschner Michael, Alzahrani Fuad M, Halawani Ibrahim F, Xiao Jianbo, Khan Haroon
Department of Pharmacy, Abdul Wali Khan University, Mardan, Mardan 23200, Pakistan.
Department of Molecular Pharmacology, Albert Einstein, College of Medicine, Bronx, NY 10463, USA.
Phytochem Rev. 2025 Apr;24(2):1119-1142. doi: 10.1007/s11101-024-09972-6. Epub 2024 May 23.
is a member of the family and important medicinal plant that is widely consumed as food in South Asia. It is commonly referred as Black Gram, Urad daal and Maash. It is traditionally used for strangulated bowel syndrome, dyspepsia, constipation, neuropathy, hepatopathy, gastritis, diarrhea, rheumatism, diabetes, etc. This review article provides up-to-date information on including its reported ethnopharmacology, pharmacological activities, phytochemistry and nutritious composition. Articles were screened from databases such as Web of Science, SpringerLink, Google Scholar, PubMed, Medline Plus, Elsevier, and Science Direct. contains phytochemical including alkaloids, flavonoids, saponins, steroids, tannins, phenolic compounds, fatty acids, carbohydrates, amino acids, vitamins, and carotenoids. These compounds exert pharmacological activities both in-vitro and in-vivo including antioxidant, antidiabetic, anti-hyperlipidemic, immunostimulatory, hepatoprotective, nephroprotective, antibacterial, anthelmintic, thrombolytic, anti-inflammatory, analgesic, ulcerogenic, anticonvulsant, nootropic, anti-osteoarthritic, aphrodisiac, spermatogenic and anticancer activities. Currently, scientific data in supports of the biological activities are scarce. We suggest more in-depth to determine its clinical efficacy.
是豆科植物的一员,是一种重要的药用植物,在南亚被广泛用作食物。它通常被称为黑绿豆、乌头豆和马什豆。传统上,它用于治疗肠梗阻综合征、消化不良、便秘、神经病变、肝病、胃炎、腹泻、风湿病、糖尿病等。这篇综述文章提供了关于它的最新信息,包括其报道的民族药理学、药理活性、植物化学和营养成分。文章从科学网、施普林格链接、谷歌学术、PubMed、医学在线 Plus、爱思唯尔和科学Direct等数据库中筛选。它含有植物化学物质,包括生物碱、黄酮类化合物、皂苷、类固醇、单宁、酚类化合物、脂肪酸、碳水化合物、氨基酸、维生素和类胡萝卜素。这些化合物在体外和体内都具有药理活性,包括抗氧化、抗糖尿病、抗高血脂、免疫刺激、保肝、保肾、抗菌、驱虫、溶栓、抗炎、镇痛、致溃疡、抗惊厥、益智、抗骨关节炎、壮阳、生精和抗癌活性。目前,支持其生物活性的科学数据很少。我们建议进行更深入的研究以确定其临床疗效。