Randrianarisoa Rova Malala Fandresena, Ravelonjatovo Mirantosoa Fabiola, Menzato Gerda, Randriamihangy Narindrarimanana Avisoa, Ralison Fidiarivony
Internal Medicine, University Hospital Joseph Raseta Befelatanana, Antananarivo, MDG.
Cardiology, Mahavoky Atsimo University Hospital, Mahajanga, MDG.
Cureus. 2025 Apr 15;17(4):e82282. doi: 10.7759/cureus.82282. eCollection 2025 Apr.
Introduction Despite the increasing development of research on atrial fibrillation (AF), epidemiologic data remain limited in certain regions, particularly Madagascar. Madagascar is a country with limited resources and data on the cardiovascular health of the population. Our objectives were to report the prevalence of AF and to describe patient characteristics. Materials and methods This was a retrospective descriptive study that included 103 patients with AF during their hospitalization at the cardiology department of the Mahavoky Atsimo University Hospital in Mahajanga between January 2015 and July 2023. Results The prevalence of AF was 5.27%. The mean age of the patients was 59.53 years (±17.88), and the sex ratio was 1.10. All patients were symptomatic, and dyspnea (53.40%; n = 55) was the main symptom. Signs of heart failure (HF) were observed in 70.87% of cases (n = 73). The majority of patients (87.38%; n = 90) had a CHADS-VASc (congestive HF, hypertension, age ≥75 years, diabetes mellitus, previous stroke, vascular disease, age 65-74 years, sex category) score ≥ 2, and of these, 10 patients were not anticoagulated. Vitamin K antagonists and direct oral anticoagulants were prescribed in 71.84% (n = 74) and 9.71% (n = 10) of cases, respectively. Rate control was the most commonly used therapeutic strategy. Spontaneous return to sinus rhythm occurred in 14 patients (13.59%). Twelve patients (11.65%) had a stroke, and one patient (0.97%) died during a mean hospital stay of 6.92 days (±4.7). Conclusions This study provides an overview of the situation in Madagascar. Management is far from meeting current recommendations for good practice, which is a major challenge.
引言 尽管心房颤动（AF）的研究不断发展，但某些地区的流行病学数据仍然有限，特别是在马达加斯加。马达加斯加是一个资源有限的国家，关于其人口心血管健康的数据也很匮乏。我们的目标是报告AF的患病率并描述患者特征。
材料与方法 这是一项回顾性描述性研究，纳入了2015年1月至2023年7月在马哈赞加市马哈沃基·阿齐莫大学医院心内科住院期间被诊断为AF的103例患者。
结果 AF的患病率为5.27%。患者的平均年龄为59.53岁（±17.88），性别比为1.10。所有患者均有症状，呼吸困难（53.40%；n = 55）是主要症状。70.87%的病例（n = 73）观察到心力衰竭（HF）体征。大多数患者（87.38%；n = 90）的CHADS-VASc（充血性HF、高血压、年龄≥75岁、糖尿病、既往卒中、血管疾病、年龄65 - 74岁、性别类别）评分≥2，其中10例患者未接受抗凝治疗。分别有71.84%（n = 74）和9.71%（n = 10）的病例使用了维生素K拮抗剂和直接口服抗凝剂。心率控制是最常用的治疗策略。14例患者（13.59%）自发恢复窦性心律。12例患者（11.65%）发生卒中，1例患者（0.97%）在平均住院6.92天（±4.7）期间死亡。
结论 本研究概述了马达加斯加的情况。管理远未达到当前良好实践的建议，这是一个重大挑战。
