Bautista-Molano Wilson
University Hospital Fundación Santa Fe de Bogotá, School of Medicine, Universidad El Bosque, Bogotá, Colombia.
Curr Opin Rheumatol. 2025 Jul 1;37(4):276-281. doi: 10.1097/BOR.0000000000001097. Epub 2025 May 14.
This review provides a critical analysis of the management of axial spondyloarthritis (axSpA) and psoriatic arthritis (PsA) in Latin America, emphasizing regional challenges, genetic diversity, healthcare disparities, and efforts to optimize patient care in resource-limited settings.
Recent literature highlights significant differences in treatment accessibility, healthcare infrastructure, and disease burden across Latin America considering the management of axSpA and PsA. Pan American league of associations for rheumatology (PANLAR) has established region-specific treatment recommendations adapted to the region that address these disparities while complementing international guidelines from assessment of spondyloarthritis international society - European alliance of associations for rheumatology (ASAS-EULAR) and group for research and assessment of psoriasis and psoriatic arthritis (GRAPPA). Limited access to biologics, high rates of diagnostic delay, and unique genetic and environmental factors shape disease management in this region. From the clinical perspective, the higher frequency of peripheral manifestations and the low frequency of HLA-B27 are remarkable.
Latin America faces distinct obstacles in axSpA and PsA management, requiring tailored strategies that integrate regional epidemiological characteristics, healthcare system disparities, and economic constraints. Supporting collaborative research networks across all countries and increasing access to advanced therapies are critical to enhance patient outcomes in SpA and PsA. Implementation of management strategies in the continent are required.
本综述对拉丁美洲中轴型脊柱关节炎(axSpA)和银屑病关节炎(PsA)的管理进行批判性分析,重点关注区域挑战、遗传多样性、医疗保健差异以及在资源有限环境中优化患者护理的努力。
最近的文献强调,考虑到axSpA和PsA的管理,拉丁美洲各地在治疗可及性、医疗基础设施和疾病负担方面存在显著差异。泛美风湿病协会联盟(PANLAR)制定了适应该地区的特定治疗建议,以解决这些差异,同时补充来自脊柱关节炎国际协会-欧洲风湿病协会联盟(ASAS-EULAR)和银屑病及银屑病关节炎研究与评估小组(GRAPPA)的国际指南。生物制剂获取受限、诊断延迟率高以及独特的遗传和环境因素影响着该地区的疾病管理。从临床角度来看,外周表现频率较高和HLA-B27频率较低值得关注。
拉丁美洲在axSpA和PsA管理方面面临独特障碍,需要制定综合区域流行病学特征、医疗系统差异和经济限制的定制策略。支持各国之间的合作研究网络以及增加获得先进疗法的机会对于改善SpA和PsA患者的结局至关重要。需要在该大陆实施管理策略。