Suppr超能文献

打开心扉:印度东北部一家三级护理中心对缩窄性心包炎的干预措施及结果的10年经验

Unlocking the Heart: A 10-Year Experience of Interventions and Outcomes of Constrictive Pericarditis in a Northeast Indian Tertiary Care Center.

作者信息

Kynta Reuben L, Rawat Sanjib, Bharadwaj Rajeev, Goyal Abhilash

机构信息

Department of Cardiothoracic and Vascular Surgery, North Eastern Indira Gandhi Regional Institute of Health and Medical Sciences, Shillong, IND.

Department of Cardiothoracic and Vascular Surgery, All India Institute of Medical Sciences, Guwahati, Guwahati, IND.

出版信息

Cureus. 2025 Apr 16;17(4):e82369. doi: 10.7759/cureus.82369. eCollection 2025 Apr.

Abstract

INTRODUCTION

Chronic constrictive pericarditis (CCP) is a debilitating condition characterized by thickening and fibrosis of the pericardium, leading to impaired diastolic filling and reduced cardiac output. Patients typically present with symptoms of right-sided heart failure, such as peripheral edema, ascites, and dyspnea. Definitive treatment involves surgical pericardiectomy, which aims to remove the constrictive pericardium and restore normal cardiac function. This study aims to assess the operative and short-term outcome of this rare disease in the northeastern part of India.

METHODS

Retrospective data records of patients who underwent pericardiectomy were analyzed from 2011 to 2020.

RESULTS

Of the patients, 20 (47.6%) were in New York Heart Association (NYHA) class III, and 12 (28.6%) were in NYHA class IV. Hyperbilirubinemia was seen in 29 (69%) patients, and hypoalbuminemia in 18 (42.9%) patients. Radical pericardiectomy was done in 36 (85.7%) cases, and the waffle operation was done in five (12%) cases. The mean ICU stay post procedure was 5.81 days (2-18 days), and the mean hospital stay was 19.6 days (2-49 days). The in-hospital mortality rate was 14.6% (six cases), and the cause of death in all cases was persistent low cardiac output.

CONCLUSION

Pericardiectomy is the only definitive treatment for symptomatic CCP, and it gives a chance to the patient for a full recovery from the chronic morbidity and mortality it is associated with. The right time for surgical intervention is still not clear and needs to be individualized for each patient, but the earlier the intervention, the better the short-term survival.

摘要

引言

慢性缩窄性心包炎(CCP)是一种使人衰弱的疾病,其特征为心包增厚和纤维化,导致舒张期充盈受损和心输出量减少。患者通常表现为右心衰竭症状,如外周水肿、腹水和呼吸困难。明确的治疗方法是心包切除术,其目的是切除缩窄的心包并恢复正常心脏功能。本研究旨在评估这种罕见疾病在印度东北部的手术及短期预后。

方法

分析2011年至2020年接受心包切除术患者的回顾性数据记录。

结果

在这些患者中,20例(47.6%)处于纽约心脏协会(NYHA)III级,12例(28.6%)处于NYHA IV级。29例(69%)患者出现高胆红素血症,18例(42.9%)患者出现低蛋白血症。36例(85.7%)患者进行了根治性心包切除术,5例(12%)患者进行了网格状手术。术后平均重症监护病房(ICU)住院时间为5.81天(2 - 18天),平均住院时间为19.6天(2 - 49天)。院内死亡率为14.6%(6例),所有病例的死亡原因均为持续性低心输出量。

结论

心包切除术是有症状的CCP的唯一明确治疗方法,它为患者提供了从与之相关的慢性发病率和死亡率中完全康复的机会。手术干预的最佳时机仍不明确,需要针对每个患者进行个体化评估,但干预越早,短期生存率越好。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验