De Weerdt Sonia, Schotte C, Demolder F, Verbanck S, Verbraecken J
Sleep Laboratory, Respiratory Division, UZ Brussels, Sleep laboratory, Laarbeeklaan 101, Jette, 1090, Belgium.
Faculty of Psychology and Educational al Sciences, Brussels University Consultation Center (BRUCC), Vrije Universiteit Brussel, Brussels, Belgium.
Sleep Breath. 2025 May 19;29(3):189. doi: 10.1007/s11325-025-03352-w.
To determine the influence of type D personality on the prevalence of cardiovascular diseases (CVD), anxiety, depression, sleep quality and insomnia in OSA patients.
Patients planned for a polysomnography filled out the DS-14 questionnaire, Hospital Anxiety and Depression Scale (HADS), Insomnia Severity Index (ISI) and Pittsburgh Sleep Quality Index (PSQI). History of cardiovascular diseases and current medication intake were assessed.
In a cohort of 948, OSA patients with type D personality did not have CVD more often (40%) compared to OSA patients without type D personality (42%) (P = 0.625). Out of 395 patients with OSA and CVD, 70% were treated for isolated arterial hypertension (AHT) and 30% for cerebrovascular and/or cardiac pathologies. Cerebrovascular and/or cardiac pathologies were significantly more prevalent in OSA patients with type D personality vs. without (39% vs. 26%; P = 0.001). In OSA patients with CVD and type D personality, medication intake was significantly higher (> 2 cardiovascular medications (P = 0.009), anxiolytics (P = 0.001), antidepressants (P = 0.011), sleep medication (P = 0.002)) as well as scores of HADS for anxiety (P < 0.0001) and depression (P < 0.0001), ISI (P = < 0.0001) and PSQI (P < 0.0001).
The prevalence of CVD in OSA patients was not related to the presence of type D personality. Apart from arterial hypertension, cerebrovascular and/or cardiac pathologies were more frequently observed in OSA patients with type D personality. In OSA patients with CVD, the presence of type D personality was associated with more depression, anxiety, insomnia, poor sleep quality and more medication intake.
确定D型人格对阻塞性睡眠呼吸暂停（OSA）患者心血管疾病（CVD）、焦虑、抑郁、睡眠质量和失眠患病率的影响。
计划进行多导睡眠图检查的患者填写DS - 14问卷、医院焦虑抑郁量表（HADS）、失眠严重程度指数（ISI）和匹兹堡睡眠质量指数（PSQI）。评估心血管疾病史和当前药物摄入情况。
在948例患者队列中，与非D型人格的OSA患者（42%）相比，D型人格的OSA患者患CVD的比例并不更高（40%）（P = 0.625）。在395例患有OSA和CVD的患者中，70%接受了单纯动脉高血压（AHT）治疗，30%接受了脑血管和/或心脏疾病治疗。与非D型人格的OSA患者相比，D型人格的OSA患者中脑血管和/或心脏疾病明显更为普遍（39%对26%；P = 0.001）。在患有CVD和D型人格的OSA患者中，药物摄入量明显更高（>2种心血管药物（P = 0.009）、抗焦虑药（P = 0.001）、抗抑郁药（P = 0.011）、助眠药物（P = 0.002）），以及HADS焦虑评分（P < 0.0001）、抑郁评分（P < 0.0001）、ISI评分（P = < 0.0001）和PSQI评分（P < 0.0001）。
OSA患者中CVD的患病率与D型人格的存在无关。除动脉高血压外，D型人格的OSA患者中更常观察到脑血管和/或心脏疾病。在患有CVD的OSA患者中，D型人格的存在与更多的抑郁、焦虑、失眠、睡眠质量差和更多的药物摄入有关。
