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白内障手术后脉络膜厚度变化的回顾性评估。

Retrospective evaluation of changes in choroidal thickness after cataract surgery.

作者信息

Wu Weizhen, Li Songguo, Zhang Xiaolei, Wang Luping, Wang Hongbin

机构信息

Department of Ophthalmology, Beijing Friendship Hospital, Capital Medical University, Beijing, China.

Department of Ophthalmology, Shougang Hospital, Peking University, Beijing, China.

出版信息

Eur J Med Res. 2025 May 19;30(1):397. doi: 10.1186/s40001-025-02653-w.

Abstract

In this retrospective study, we investigated the changes in choroidal thickness (CT) using enhanced depth imaging spectral domain-optical coherence tomography (EDI-OCT) and intraocular pressure (IOP) following phacoemulsification. Twenty eyes of 18 patients who underwent phacoemulsification and intraocular lens implantation were included in this study. All patients underwent a detailed ophthalmologic examination. EDI-OCT was used to measure CT preoperatively, and postoperatively at days 3 and 10, and months 1, 3, and 6. CT was measured at the fovea and at points 1.5 mm and 3.0 mm nasal and temporal to the fovea. The data were compared using one-way analysis of variance. The correlation between the changes in the CT and IOP in all sectors was analyzed. There was statistically significant change in IOP after cataract surgery (P = 0.000). The IOP reached a minimum (10.43 ± 1.64 mmHg) at 6 months postoperatively. Postoperatively CT increased significantly at three sectors: the subfovea (P = 0.019), 1.5 mm nasal to the fovea (P = 0.003), and 3 mm nasal to the fovea (P = 0.000), and gradually thickened over time, reaching a peak (288.87 ± 67.70 µm) at 6 months postoperatively. The CT increase was negatively correlated with the decrease in IOP within 6 months after surgery (P < 0.05). This study demonstrated that after cataract surgery, the IOP decreased and the choroid thickened, lasting up to 6 months. Studying the changes in CT and IOP after cataract surgery will help deepen the understanding of fundus diseases associated with cataract surgery and will also play a guiding role in solving clinical complications.

摘要

在这项回顾性研究中,我们使用增强深度成像光谱域光学相干断层扫描(EDI-OCT)研究了白内障超声乳化术后脉络膜厚度(CT)和眼压(IOP)的变化。本研究纳入了18例行白内障超声乳化及人工晶状体植入术患者的20只眼。所有患者均接受了详细的眼科检查。术前、术后第3天和第10天以及术后1、3和6个月使用EDI-OCT测量CT。在黄斑中心凹以及黄斑中心凹鼻侧和颞侧1.5 mm及3.0 mm处测量CT。采用单因素方差分析对数据进行比较。分析了所有象限CT变化与IOP之间的相关性。白内障手术后眼压有统计学意义的变化(P = 0.000)。眼压在术后6个月达到最低值(10.43±1.64 mmHg)。术后三个象限的CT显著增加:黄斑中心凹下(P = 0.019)、黄斑中心凹鼻侧1.5 mm处(P = 0.003)和黄斑中心凹鼻侧3 mm处(P = 0.000),并随时间逐渐增厚,在术后6个月达到峰值(288.87±67.70 µm)。术后6个月内CT增加与眼压降低呈负相关(P < 0.05)。本研究表明,白内障手术后眼压降低,脉络膜增厚,持续长达6个月。研究白内障手术后CT和IOP的变化将有助于加深对与白内障手术相关的眼底疾病的理解,也将对解决临床并发症起到指导作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7943/12087108/e88a470609cd/40001_2025_2653_Fig1_HTML.jpg

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