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CR和PS全膝关节置换术中期随访时的关节感知及植入物生存率比较:基于解剖学表型的倾向评分匹配分析

Comparable joint awareness and implant survival at midterm follow-up between CR and PS TKA: An anatomic phenotype-based propensity score-matched analysis.

作者信息

Tuecking Lars-Rene, Welzel Tobias, Ettinger Max, Windhagen Henning, Savov Peter

机构信息

Department of Orthopaedic Surgery Hannover Medical School, Diakovere Annastift Hannover Germany.

Department of Orthopaedic and Trauma Surgery, Pius Hospital Carl von Ossietzky University of Oldenburg Oldenburg Germany.

出版信息

J Exp Orthop. 2025 May 19;12(2):e70242. doi: 10.1002/jeo2.70242. eCollection 2025 Apr.

Abstract

PURPOSE

Recent studies highlight the role of joint awareness and the influence of preoperative anatomy on outcomes of cruciate-retaining (CR) versus posterior-stabilized (PS) implants in total knee arthroplasty (TKA). There is currently a lack of studies comparing CR and PS prostheses while adjusting for important anatomical parameters and anatomical phenotypes with large group sizes.

METHODS

This retrospective single-centre study analyzed patients who underwent primary TKA with the Triathlon® CR or PS implant system from 2008 to 2014 with a minimum follow-up of 6.5 years. Patients were matched using propensity scores based on demographics (age, gender and body mass index) and preoperative anatomic angle parameters (lateral distal femoral angle [LDFA], medial proximal tibia angle, hip-knee-ankle angle [HKA], arithmetic HKA and joint line obliquity) and Coronal Plane Alignment of the Knee (CPAK) types. Outcome data included patient-reported outcomes (PROMs: Forgotten Joint Score, Oxford Knee Score, Knee Society Score, Western Ontario and McMaster Universities Osteoarthritis Index, visual analogue scale and University of California at Los Angeles), demographic data, post-operative clinical course data. Statistical analysis was conducted using R, with significance set at  < 0.05.

RESULTS

A total of 728 patients (513 CR and 215 PS) were included, leaving 519 patients (346 CR and 173 PS) being analyzed after propensity score matching. Joint awareness and further clinical scores showed no differences between CR and PS implants ( > 0.05). Implant survival at 5 and 10 years was similar for both types (log-rank test:  = 0.164 and  = 0.163), though CR implants had lower survival rates overall. Valgus CPAK types III and VI showed the lowest survival rates, especially for CR implants. Regression analysis revealed younger patient age significantly affected CR implant survival, while increasing valgus LDFA decreased PS implant survival.

CONCLUSION

No differences were found in the joint awareness of CR and PS prostheses in the medium to long-term follow-up, while controlling for preoperative anatomy. Similarly, there were no significant variations in implant survival. Noticeably higher revision rates in the valgus CPAK phenotypes were found for both systems. A high valgus LDFA angle was identified as a risk factor for revisions in PS systems.

LEVEL OF EVIDENCE

Level III.

摘要

目的

近期研究强调了关节感知的作用以及术前解剖结构对全膝关节置换术(TKA)中保留交叉韧带(CR)与后稳定型(PS)假体结局的影响。目前缺乏在调整重要解剖参数和解剖表型且样本量较大的情况下比较CR和PS假体的研究。

方法

这项回顾性单中心研究分析了2008年至2014年接受使用Triathlon® CR或PS植入系统进行初次TKA的患者,最小随访时间为6.5年。根据人口统计学特征(年龄、性别和体重指数)、术前解剖角度参数(外侧股骨远端角[LDFA]、内侧胫骨近端角、髋-膝-踝角[HKA]、算术HKA和关节线倾斜度)以及膝关节冠状面排列(CPAK)类型,使用倾向评分对患者进行匹配。结局数据包括患者报告的结局(PROMs:遗忘关节评分、牛津膝关节评分、膝关节协会评分、西安大略和麦克马斯特大学骨关节炎指数、视觉模拟量表和加利福尼亚大学洛杉矶分校评分)、人口统计学数据、术后临床病程数据。使用R进行统计分析,显著性设定为<0.05。

结果

共纳入728例患者(513例CR和215例PS),倾向评分匹配后留下519例患者(346例CR和173例PS)进行分析。CR和PS假体之间的关节感知及进一步的临床评分无差异(>0.05)。两种类型在5年和10年时的假体生存率相似(对数秩检验:=0.164和=0.163),尽管CR假体总体生存率较低。外翻CPAK III型和VI型的生存率最低,尤其是CR假体。回归分析显示,患者年龄较小显著影响CR假体生存率,而外翻LDFA增加会降低PS假体生存率。

结论

在中长期随访中,在控制术前解剖结构的情况下,CR和PS假体的关节感知无差异。同样,假体生存率也无显著差异。两种系统在外翻CPAK表型中的翻修率均明显较高。高外翻LDFA角被确定为PS系统翻修的危险因素。

证据水平

III级。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4784/12086798/8669c017aac4/JEO2-12-e70242-g002.jpg

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