Evidence Summary of Personalized Management of Peritoneal Dialysis Volume in Adults.

PURPOSE

The overload capacity poses great challenges to the management and prognosis of peritoneal dialysis patients. There have been many studies, but they are relatively fragmented and inconsistent. It is urgent to summarize high-quality evidence. The objective of this study is to thoroughly investigate, extract, assess, and synthesize the most relevant evidence about the individualized management of peritoneal volume in patients undergoing peritoneal dialysis. It can be utilized in clinical practice to improve patient outcomes.

METHODS

The study used the "6S" pyramid model to identify all available evidence related to the personalized management of peritoneal volume among patients receiving peritoneal dialysis. This comprehensive search encompassed various types of evidence, including guidelines, recommended practices, systematic reviews, evidence summaries, expert consensus documents, and original research studies. These were sourced from both domestic and international guideline websites, professional association platforms, as well as relevant databases. The time limit was set from the date of database creation until April 2024, with the search commencing in December 2023.

RESULTS

The systematic search yielded 17 pieces of literature that were ultimately included in the analysis. This collection comprised seven guidelines, four best practices, two documents reflecting expert consensus, two systematic reviews, and two randomized controlled trials. The overall quality of the literature analyzed was found to be high. Through this thorough review, a total of 37 pieces of the best evidence were identified and categorized into three critical aspects: risk factors, comprehensive assessment methodologies, and various intervention strategies.

CONCLUSION

This study serves as a consolidation of the available evidence regarding the personalized management of peritoneal volume for patients undergoing peritoneal dialysis. It underscores the importance of clinical staff's ability to implement tailored volume management programs that address the unique circumstances of each patient.